SCHEMBL5136339

SCHEMBL5136339

O[C@H](CN(Cc1ccc(C(F)(F)F)cc1F)c1cccc(Oc2cccc(OC(F)F)c2)c1)C(F)F

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 19/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL993609 0.90 CETP (0.70) CETP
SCHEMBL993483 0.90 CETP (0.70) CETP
SCHEMBL6304522 0.84 CETP (0.59) CETP
SCHEMBL993209 0.83 CETP (0.70) CETP
SCHEMBL992339 0.83 CETP (0.70) CETP
SCHEMBL992557 0.82 CETP (0.72) CETP
SCHEMBL994112 0.82 CETP (0.72) CETP
SCHEMBL994078 0.82 CETP (0.71) CETP
SCHEMBL992644 0.82 CETP (0.71) CETP
SCHEMBL994919 0.80 CETP (0.75) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1578415-B1 DOSAGE FORMS COMPRISING A CETP INHIBITOR AND AN HMG-COA REDUCTASE INHIBITOR PFIZER PROD INC (US) 2008-09-10 EP disclosed