SCHEMBL5136364

SCHEMBL5136364

COc1ccc(Oc2ccc3c(O)c(C(=O)[AsH]CC(=O)O)ncc3c2)cc1

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EGLN2 Q96KS0 17/20 0.63
EGLN1 Q9GZT9 14/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL522758 0.80 EGLN1 (0.84) EGLN2EGLN1
SCHEMBL15268444 0.80 EGLN2 (0.65) EGLN2EGLN1
SCHEMBL5314140 0.80 EGLN2 (0.62) EGLN2EGLN1
SCHEMBL5314146 0.80 EGLN2 (0.62) EGLN2EGLN1
SCHEMBL15268493 0.77 EGLN2 (1.00) EGLN2EGLN1
SCHEMBL15268661 0.76 EGLN2 (1.00) EGLN2EGLN1
SCHEMBL522048 0.76 EGLN2 (0.59) EGLN2EGLN1
SCHEMBL523000 0.75 EGLN2 (0.70) EGLN2EGLN1
SCHEMBL523001 0.75 EGLN2 (0.70) EGLN2EGLN1
SCHEMBL15268934 0.75 EGLN2 (1.00) EGLN2EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1893186-A2 IMPROVED TREATMENT FOR ANEMIA USING A HIF-ALPHA STABILISING AGENT FIBROGEN, INC. (US) 2008-03-05 EP disclosed
WO-2007146425-A2 COMPOUNDS AND METHODS FOR TREATMENT OF CHEMOTHERAPY-INDUCED ANEMIA FIBROGEN, INC. (US) 2007-12-21 WO disclosed
WO-2006133391-A2 IMPROVED TREATMENT FOR ANEMIA USING A HIF-ALPHA STABILISING AGENT FIBROGEN, INC. (US) 2006-12-14 WO disclosed