Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13244728 | 0.69 | KCNH2 (0.71) | KCNH2 | |
| SCHEMBL13266838 | 0.68 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL14461107 | 0.68 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL3154039 | 0.68 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL2767082 | 0.67 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL2766739 | 0.66 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL4658853 | 0.64 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL13266820 | 0.64 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL2936412 | 0.59 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL3109297 | 0.57 | DAO (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963324-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND THEIR USE AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007071936-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND THEIR USE AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2007-06-28 | — | — | WO | disclosed |