Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5072780 | 0.90 | TACR2 (0.48) | TACR2 | |
| SCHEMBL5072781 | 0.90 | TACR2 (0.48) | TACR2 | |
| SCHEMBL4255121 | 0.89 | TACR2 (0.51) | TACR2 | |
| SCHEMBL5799585 | 0.89 | TACR2 (0.51) | TACR2 | |
| SCHEMBL5073372 | 0.88 | TACR2 (0.49) | TACR2CCR5 | |
| SCHEMBL4260405 | 0.86 | TACR2 (0.63) | TACR2 | |
| SCHEMBL5312978 | 0.86 | TACR2 (0.63) | TACR2 | |
| Hydrochloric Acid SCHEMBL4259647 | 0.85 | TACR2 (0.62) | TACR2 | |
| SCHEMBL5076571 | 0.83 | TACR2 (0.45) | TACR2CCR5 | |
| SCHEMBL493752 | 0.81 | TACR2 (0.44) | TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899318-A1 | NEW AZETIDINE DERIVATIVES AS NEUROKININ RECEPTOR ANTAGONISTS FOR THE TREATMENT OF GASTROINTESTINAL DISEASES | AstraZeneca AB (SE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2006137791-A1 | NEW AZETIDINE DERIVATIVES AS NEUROKININ RECEPTOR ANTAGONISTS FOR THE TREATMENT OF GASTROINTESTINAL DISEASES | ASTRAZENECA AB (SE) | 2006-12-28 | — | — | WO | disclosed |