Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | FABP7 | O15540 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7648282 | 0.89 | ELANE (0.47) | ELANEATML3MBTL1MAPTPRTN3 | |
| SCHEMBL28008255 | 0.77 | ELANE (0.47) | ELANEATML3MBTL1MAPTPRTN3 | |
| SCHEMBL27926031 | 0.75 | ELANE (0.46) | ELANEATML3MBTL1MAPTMAOB | |
| SCHEMBL9937133 | 0.74 | HTT (0.33) | HTT | |
| SCHEMBL28008260 | 0.74 | ELANE (0.49) | ELANEATML3MBTL1MAPTNPSR1 | |
| SCHEMBL28245989 | 0.74 | ELANE (0.45) | ELANEATML3MBTL1MAPTMAOB | |
| SCHEMBL29281054 | 0.74 | POLB (0.49) | ATML3MBTL1MAPTLMNANPSR1 | |
| SCHEMBL14946654 | 0.73 | ELANE (0.47) | ELANEATML3MBTL1MAPTMAOB | |
| SCHEMBL539078 | 0.73 | ELANE (0.50) | ELANEATML3MBTL1MAPTNPSR1 | |
| SCHEMBL131278 | 0.73 | ELANE (0.51) | ELANEATML3MBTL1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966204-A1 | NOVEL HETEROCYCLIC OXIME DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Les Laboratoires Servier (FR) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007077313-A1 | NOVEL HETEROCYCLIC OXIME DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2007-07-12 | — | — | WO | disclosed |