Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 4/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16298859 | 1.00 | CA1 (0.57) | CA1ACE2ZDHHC7TP53OPRM1 | |
| SCHEMBL8963949 | 0.98 | CA1 (0.55) | CA1ACE2ZDHHC7TP53FDPS | |
| SCHEMBL3677429 | 0.98 | CA1 (0.55) | CA1ACE2ZDHHC7TP53FDPS | |
| SCHEMBL8073537 | 0.98 | CA1 (0.55) | CA1ACE2ZDHHC7TP53FDPS | |
| SCHEMBL3673850 | 0.98 | CA1 (0.55) | CA1ACE2ZDHHC7TP53FDPS | |
| SCHEMBL11869095 | 0.98 | CA1 (0.55) | CA1ACE2ZDHHC7TP53FDPS | |
| SCHEMBL22748707 | 0.98 | CA1 (0.55) | CA1ACE2ZDHHC7TP53FDPS | |
| SCHEMBL14169844 | 0.98 | CA1 (0.55) | CA1ACE2ZDHHC7TP53FDPS | |
| SCHEMBL6117662 | 0.98 | CA1 (0.55) | CA1ACE2ZDHHC7TP53FDPS | |
| Hydrochloric Acid SCHEMBL28426136 | 0.96 | CA1 (0.53) | CA1ACE2ZDHHC7TP53FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936144-B | JAK inhibitors | 廖细斌 | 2023-12-22 | — | — | CN | claimed |
| CN-112154145-B | Piperazine azaspiro derivatives | 辉瑞大药厂 | 2023-10-17 | — | — | CN | claimed |
| CN-110944992-B | Pharmaceutical compounds | 赫普泰雅治疗有限公司 | 2023-05-16 | — | — | CN | claimed |
| CN-107949558-B | Muscarinic agonists | 赫普泰雅治疗有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-109790179-B | Composition for hardening soft tissue | 加图立大学校产学协力团 | 2022-01-14 | — | — | CN | claimed |
| CN-112154145-A | Piperazine azaspiro derivatives | 辉瑞大药厂 | 2020-12-29 | — | — | CN | claimed |
| CN-107406449-B | Spiro compounds as agonists of the muscarinic M1 receptor and/or M4 receptor | 赫普泰雅治疗有限公司 | 2020-11-10 | — | — | CN | claimed |
| CN-110944992-A | Pharmaceutical compounds | 赫普泰雅治疗有限公司 | 2020-03-31 | — | — | CN | claimed |
| CN-101312952-B | Tetrahydro-cyclopentapyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA NV | 2012-12-26 | — | — | CN | claimed |
| CN-101312952-A | Tetrahydro-cyclopentapyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA NV (BE) | 2008-11-26 | — | — | CN | claimed |
| CN-118201921-A | Lactams as CBL-B inhibitors selective for C-CBL | 基因泰克公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-113166149-B | Compounds for the treatment of type II diabetes | 尼奥比奥特克有限责任公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-117551037-A | Compounds as succinate dehydrogenase inhibitors and uses thereof | 华东理工大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-117440813-A | EGFR degrading agents for treating brain or CNS cancer metastasis | C4医药公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-111936144-B | JAK inhibitors | 廖细斌 | 2023-12-22 | — | — | CN | disclosed |
| EP-0278105-B1 | 2,4,4-TRI- AND 2,2,4,4-TETRA-SUBSTITUTED-1,3-DIOXOLANE | SCHERING CORP (US) | 1992-05-06 | — | — | EP | disclosed |
| EP-0329711-A1 | 2,4,4-TRI- AND 2,2,4,4-TETRA SUBSTITUTED-1,3-DIOXOLANE COMPOUNDS | SCHERING CORPORATION (US) | 1989-08-30 | — | — | EP | disclosed |
| US-4788190-A | 2,4,4-tri- and 2,2,4,4-tetra substituted-1,3-dioxolane antifungal, antiallergy compounds | SCHERING CORPORATION (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0278105-A1 | 2,4,4-Tri- and 2,2,4,4-tetra-substituted-1,3-dioxolane | SCHERING CORPORATION (US) | 1988-08-17 | — | — | EP | disclosed |
| WO-1988005048-A1 | 2,4,4-TRI- AND 2,2,4,4-TETRA SUBSTITUTED-1,3-DIOXOLANE COMPOUNDS | SCHERING CORPORATION (US) | 1988-07-14 | — | — | WO | disclosed |