⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13656487 | 0.79 | TSHR (0.43) | — | |
| SCHEMBL4263883 | 0.79 | — | — | |
| SCHEMBL5067712 | 0.79 | TSHR (0.43) | — | |
| SCHEMBL5056943 | 0.79 | CYP1A2 (0.46) | — | |
| SCHEMBL8869648 | 0.77 | — | — | |
| SCHEMBL21001195 | 0.75 | — | — | |
| SCHEMBL27918240 | 0.75 | — | — | |
| SCHEMBL6161509 | 0.75 | — | — | |
| 2-Acetylpyrrole SCHEMBL150349 | 0.75 | — | — | |
| SCHEMBL6158158 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305900-B1 | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES | NUEVOLUTION AS (DK) | 2021-07-21 | — | — | EP | disclosed |
| CN-110036047-B | Methacrylic copolymer and molded article | 株式会社可乐丽 | 2021-01-05 | — | — | CN | disclosed |
| EP-3305900-A1 | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES | Nuevolution A/S (DK) | 2018-04-11 | — | — | EP | disclosed |
| EP-2341140-B1 | Enzymatic encoding methods for efficient synthesis of large libraries | NUEVOLUTION AS (DK) | 2017-07-19 | — | — | EP | disclosed |
| US-20160299450-A1 | CHARGING MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2016-10-13 | — | — | US | disclosed |
| WO-2015144688-A1 | HOST DEPENDENCY FACTORS AS TARGETS FOR ANTIVIRAL THERAPY | Ruprecht-Karls-Universität Heidelberg (DE) | 2015-10-01 | — | — | WO | disclosed |
| EP-1893612-A1 | PYRROLO [2, 3-B]PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | PLEXXIKON, INC. (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2007002433-A1 | PYRROLO [2, 3-B] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | PLEXXIKON, INC. (US) | 2007-01-04 | — | — | WO | disclosed |