Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 5/20 | 0.64 |
| ▸ | KIT | P10721 | 4/20 | 0.64 |
| ▸ | BRAF | P15056 | 11/20 | 0.60 |
| ▸ | RAF1 | P04049 | 1/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.53 |
| ▸ | ABL1 | P00519 | 2/20 | 0.53 |
| ▸ | SRC | P12931 | 2/20 | 0.53 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.53 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 2/20 | 0.53 |
| ▸ | BTK | Q06187 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5140117 | 0.80 | LCK (0.65) | CSF1RKITRAF1KDRMAPK14 | |
| SCHEMBL3619878 | 0.76 | CSF1R (0.69) | CSF1RKITBRAFRAF1PDGFRB | |
| SCHEMBL17992413 | 0.75 | BRAF (1.00) | CSF1RKITBRAFKDRMAPK14 | |
| SCHEMBL29772692 | 0.74 | CSF1R (1.00) | CSF1RKITBRAFRAF1MAPK14 | |
| SCHEMBL29772695 | 0.74 | CSF1R (1.00) | CSF1RKITBRAFRAF1MAPK14 | |
| SCHEMBL18164577 | 0.73 | MAPK14 (0.75) | CSF1RKITBRAFRAF1PDGFRB | |
| SCHEMBL22145723 | 0.73 | BRAF (0.67) | CSF1RKITBRAFRAF1PDGFRB | |
| SCHEMBL19073209 | 0.73 | BRAF (0.73) | CSF1RKITBRAFMAPK14ABL1 | |
| SCHEMBL16735227 | 0.72 | BRAF (0.73) | CSF1RKITBRAFRAF1PDGFRB | |
| SCHEMBL18164405 | 0.72 | BMX (0.83) | CSF1RKITBRAFKDRMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080300245-A1 | Pyrazolo[1,5-A]Pyridine-3-Carboxylic Acids as Ephb and Vegfr2 Kinase Inhibitors | IMBACH PATRICIA | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300245-A1 | Pyrazolo[1,5-A]Pyridine-3-Carboxylic Acids as Ephb and Vegfr2 Kinase Inhibitors | EPHB2, EPHB1, EPHB3 | CSF1R 476/4885KIT 133/4885BRAF 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.