Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.40 |
| ▸ | SELE | P16581 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16639666 | 0.83 | CREBBP (0.48) | CREBBPEP300ICAM1SELEEPHX2 | |
| SCHEMBL14949940 | 0.77 | CREBBP (0.41) | CREBBPEP300ICAM1SELEEPHX2 | |
| SCHEMBL18121639 | 0.76 | CREBBP (0.42) | CREBBPEP300ICAM1SELEEPHX2 | |
| SCHEMBL3809200 | 0.75 | KMT2A (0.48) | CREBBPEP300ICAM1SELENPC1 | |
| SCHEMBL10007917 | 0.74 | ICAM1 (0.45) | CREBBPEP300ICAM1SELENPC1 | |
| SCHEMBL22859636 | 0.74 | ICAM1 (0.39) | CREBBPEP300ICAM1SELEEPHX2 | |
| SCHEMBL13204747 | 0.74 | POLB (0.42) | CREBBPEP300NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4317051 | 0.73 | ICAM1 (0.45) | CREBBPEP300ICAM1SELENPC1 | |
| SCHEMBL3811958 | 0.73 | KMT2A (0.64) | CREBBPEP300ICAM1SELENPC1 | |
| SCHEMBL20857107 | 0.72 | KMT2A (0.45) | CREBBPEP300ICAM1SELEEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016159666-A2 | CRYSTAL FORM AND PREPARATION METHOD THEREFOR | 대원제약주식회사 | 2016-10-06 | — | — | WO | disclosed |
| EP-1948598-A1 | PROCESS FOR PREPARATION OF (3R, 5R)-7-[2-(4-FLUOROPHENYL)-5-ISOPROPYL-3-PHENYL-4-[(4-HYDROXY METHYL PHENYL AMINO) CARBONYL]-PYRROL-1-YL]-3,5-DIHYDROXY-HEPTANOIC ACID HEMI CALCIUM SALT | RANBAXY LABORATORIES, LTD. (IN) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007054790-A1 | PROCESS FOR PREPARATION OF (3R, 5R)-7-[2-(4-FLUOROPHENYL)-5-ISOPROPYL-3-PHENYL-4-[(4-HYDROXY METHYL PHENYL AMINO) CARBONYL]-PYRROL-1-YL]-3,5-DIHYDROXY-HEPTANOIC ACID HEMI CALCIUM SALT | RANBAXY LABORATORIES LIMITED (IN) | 2007-05-18 | — | — | WO | disclosed |