Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9413960 | 0.98 | CYP2C19 (0.54) | CYP2C19KCNN4HIF1AALDH1A1TAAR1 | |
| Hydrochloric Acid SCHEMBL9413928 | 0.96 | CYP2C19 (0.53) | CYP2C19KCNN4HIF1AALDH1A1TAAR1 | |
| SCHEMBL9413932 | 0.92 | CYP2C19 (0.50) | CYP2C19KCNN4HIF1AALDH1A1TAAR1 | |
| SCHEMBL10156588 | 0.80 | CYP2C19 (0.50) | CYP2C19KCNN4HIF1AALDH1A1TAAR1 | |
| SCHEMBL3444934 | 0.80 | KCNN4 (0.44) | CYP2C19KCNN4HIF1AALDH1A1TAAR1 | |
| SCHEMBL5035455 | 0.80 | MEN1 (0.53) | CYP2C19KCNN4ALDH1A1KMT2AMEN1 | |
| SCHEMBL8028843 | 0.79 | TAAR1 (0.56) | CYP2C19KCNN4HIF1AALDH1A1TAAR1 | |
| SCHEMBL28333306 | 0.79 | CYP2C19 (0.53) | CYP2C19HIF1AALDH1A1TAAR1ALOX15 | |
| SCHEMBL2013207 | 0.79 | CYP2C19 (0.53) | CYP2C19KCNN4HIF1AALDH1A1TAAR1 | |
| SCHEMBL16312162 | 0.79 | NPSR1 (0.55) | CYP2C19HIF1ATAAR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043037-A1 | PYRIMIDINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | SANOFI-AVENTIS (FR) | 2007-02-22 | — | — | US | claimed |
| EP-1527034-A1 | A PROCESS FOR THE OPTICAL RESOLUTION OF A PRECURSOR OF SCLAREOLIDE | FIRMENICH SA (CH) | 2005-05-04 | — | — | EP | disclosed |
| WO-2004013069-A1 | A PROCESS FOR THE OPTICAL RESOLUTION OF A PRECURSOR OF SCLAREOLIDE | FIRMENICH SA (CH) | 2004-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043037-A1 | PYRIMIDINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | HCRTR2, HCRTR1, NPY1R | CYP2C19 1021/4885KCNN4 3101/4885HIF1A 298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.