Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 9/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.48 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3037107 | 0.89 | MAP3K5 (0.56) | MAP3K5MEN1KMT2AUSP2DNMT1 | |
| SCHEMBL3037108 | 0.89 | MAP3K5 (0.56) | MAP3K5MEN1KMT2AUSP2DNMT1 | |
| SCHEMBL3036203 | 0.89 | MAP3K5 (0.53) | MAP3K5MEN1KMT2AUSP2DNMT1 | |
| SCHEMBL3036202 | 0.85 | MAP3K5 (0.55) | MAP3K5MEN1KMT2AUSP2DNMT1 | |
| SCHEMBL3036199 | 0.85 | MAP3K5 (0.55) | MAP3K5MEN1KMT2AUSP2DNMT1 | |
| SCHEMBL3042959 | 0.84 | DUSP22 (0.63) | MAP3K5MEN1KMT2AUSP2DNMT1 | |
| SCHEMBL13220195 | 0.84 | DUSP22 (0.63) | MAP3K5MEN1KMT2AUSP2DNMT1 | |
| SCHEMBL3034569 | 0.83 | DUSP22 (0.62) | MAP3K5MEN1KMT2AUSP2DNMT1 | |
| SCHEMBL3033762 | 0.83 | MAP3K5 (0.53) | MAP3K5MEN1KMT2AUSP2DNMT1 | |
| SCHEMBL3033764 | 0.83 | MAP3K5 (0.53) | MAP3K5MEN1KMT2AUSP2DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008005651-A2 | CYCLIC CARBOXYLIC ACID RHODANINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF TUBERCULOSIS | DECODE CHEMISTRY, INC. (US) | 2008-01-10 | — | — | WO | disclosed |