⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5142688 | 1.00 | — | — | |
| SCHEMBL14354959 | 1.00 | — | — | |
| SCHEMBL5142689 | 1.00 | — | — | |
| SCHEMBL5141501 | 0.87 | TRPV1 (0.59) | — | |
| SCHEMBL5141495 | 0.87 | TRPV1 (0.59) | — | |
| SCHEMBL14354957 | 0.87 | TRPV1 (0.59) | — | |
| SCHEMBL5141500 | 0.87 | TRPV1 (0.59) | — | |
| SCHEMBL5141516 | 0.84 | — | — | |
| SCHEMBL5141537 | 0.84 | TRPV1 (0.64) | — | |
| SCHEMBL14354969 | 0.84 | TRPV1 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7301022-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2007-11-27 | — | — | US | disclosed |
| US-20060183745-A1 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. | 2006-08-17 | — | — | US | disclosed |