Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5143030 | 1.00 | GRM5 (0.44) | GRM5CYP11B1CYP11B2NOTUMTRPM5 | |
| SCHEMBL10104188 | 0.88 | GRM5 (0.44) | GRM5CYP11B1CYP11B2NOTUMTRPM5 | |
| SCHEMBL19903927 | 0.86 | GRM5 (0.42) | GRM5CYP11B1CYP11B2NOTUMTRPM5 | |
| SCHEMBL15337731 | 0.84 | GRM5 (0.41) | GRM5CYP11B1CYP11B2NOTUMTRPM5 | |
| SCHEMBL13208462 | 0.84 | GRM5 (0.45) | GRM5CYP11B1CYP11B2NOTUMTRPM5 | |
| SCHEMBL14392871 | 0.82 | GRM5 (0.44) | GRM5CYP11B1CYP11B2NOTUMTRPM5 | |
| SCHEMBL13695027 | 0.82 | HDAC4 (0.45) | GRM5CYP11B1CYP11B2NOTUMTRPM5 | |
| SCHEMBL14392938 | 0.81 | GRM5 (0.38) | GRM5CYP11B1CYP11B2NOTUMTRPM5 | |
| SCHEMBL16070379 | 0.80 | GRM5 (0.38) | GRM5CYP11B1CYP11B2NOTUMTRPM5 | |
| SCHEMBL14392868 | 0.79 | MAPT (0.44) | NOTUMMAPTALDH1A1PDE10AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205680-B1 | DICHROMOPHORE CARBONYL OR HETEROCYCLIC DYE, DYE COMPOSITION COMPRISING THIS DYE, PROCESS FOR DYEING KERATIN MATERIALS USING THIS DYE | OREAL (FR) | 2012-06-27 | — | — | EP | disclosed |
| WO-2009040355-A2 | DICHROMOPHORE CARBONYL OR HETEROCYCLIC DYE, DYE COMPOSITION COMPRISING THIS DYE, PROCESS FOR DYEING KERATIN MATERIALS USING THIS DYE | L'OREAL (FR) | 2009-04-02 | — | — | WO | disclosed |
| WO-2007110541-A2 | DYEING COMPOSITION CONTAINING A THIOL/DISULPHIDE FLUORESCENT COLORANT COMPRISING A CONDENSED CYCLE, WITH AN INTERNAL CATIONIC CHARGE, AND METHOD FOR LIGHTENING KERATIN MATERIALS USING SAID COLORANT | L'OREAL (FR) | 2007-10-04 | — | — | WO | disclosed |
| WO-2007110541-A2 | DYEING COMPOSITION CONTAINING A THIOL/DISULPHIDE FLUORESCENT COLORANT COMPRISING A CONDENSED CYCLE, WITH AN INTERNAL CATIONIC CHARGE, AND METHOD FOR LIGHTENING KERATIN MATERIALS USING SAID COLORANT | L'OREAL (FR) | 2007-10-04 | — | — | WO | disclosed |