SCHEMBL514405

SCHEMBL514405

[CH2]C(=O)CBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1335608 0.73
SCHEMBL6003594 0.72
Bromoacetic Acid SCHEMBL9563093 0.70
Bromo Acetone SCHEMBL28606650 0.67
Bromoacetic Acid SCHEMBL1332022 0.67
Bromoacetic Acid SCHEMBL7617676 0.67
SCHEMBL180158 0.67
SCHEMBL34263 0.67
SCHEMBL672600 0.67
Bromoacetic Acid SCHEMBL1332313 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110551169-B Glycyrrhetinic acid derivative and preparation method and application thereof 陈昱西 2022-07-15 CN claimed
CN-110551169-A Glycyrrhetinic acid derivative and preparation method and application thereof CHEN YUXI 2019-12-10 CN claimed
WO-2023210623-A1 HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME 株式会社エス・ディー・エス バイオテック 2023-11-02 WO disclosed
CN-110551169-B Glycyrrhetinic acid derivative and preparation method and application thereof 陈昱西 2022-07-15 CN disclosed
CN-110551169-A Glycyrrhetinic acid derivative and preparation method and application thereof CHEN YUXI 2019-12-10 CN disclosed
CN-106458923-B Heterocyclic compound 株式会社大熊制药 2019-09-10 CN disclosed
CN-108778273-A bicyclic aryl monocyclic β -lactam compounds and methods of use thereof for treating bacterial infections 默沙东公司 2018-11-09 CN disclosed
CN-108738320-A 4- amino -2- (1H- pyrazolos [3 as the cGMP conditioning agents for treating angiocardiopathy, 4-b] pyridin-3-yl) -6- oxos -6,7- dihydro -5H- pyrrolo-es [2,3-d] pyrimidine derivatives and respective (1H- indazole -3- bases) derivative 默沙东公司 2018-11-02 CN disclosed
CN-107428725-A Novel heterocyclic compound, its preparation method and the pharmaceutical composition for including it 株式会社大熊制药 2017-12-01 CN disclosed
CN-106518856-A Pyrazine derivatives useful as inhibitors of ATR kinase 沃泰克斯药物股份有限公司 2017-03-22 CN disclosed
CN-106496209-A It is used as the compound of ATR kinase inhibitors 沃泰克斯药物股份有限公司 2017-03-15 CN disclosed
US-7037669-B2 Assays for amphetamine and methamphetamine using stereospecific reagents DADE BEHRING INC. (US) 2006-05-02 US disclosed
WO-2005093417-A1 ASSAYS FOR AMPHETAMINE AND METHAMPHETAMINE USING STEREOSPECIFIC REAGENTS DADE BEHRING INC. (US) 2005-10-06 WO disclosed
US-20050208603-A1 Using enzyme complexes; forming antibodies; measuring signals; calibration SIEMENS HEALTHCARE DIAGNOSTICS INC. 2005-09-22 US disclosed
CN-1639139-A 5-phenylthiazole derivatives and use as PI3 kinase inhibitors NOVARTIS AG (CH) 2005-07-13 CN disclosed
CN-1056828-C Preparation process for esters of 2,2-dimethyl 3-{(Z) 1-propenyl} cyclopropane carboxylic acid and intermediates ROUSSEL UCLAF (FR) 2000-09-27 CN disclosed
EP-0282895-B1 2-oxa-isocephem compounds, compositions containing same and processes for preparing same OTSUKA PHARMA CO LTD (JP) 1995-06-07 EP disclosed
US-5037976-A Antimicrobial Agent OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-08-06 US disclosed
US-4898859-A 2-Oxa-isocephem compounds and compositions containing same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-02-06 US disclosed
EP-0282895-A2 2-oxa-isocephem compounds, compositions containing same and processes for preparing same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-09-21 EP disclosed