Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.52 |
| ▸ | CA2 | P00918 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27746898 | 0.83 | MAPT (0.49) | CA1CA2MAPTCES2CES1 | |
| SCHEMBL4232572 | 0.83 | CA1 (0.52) | CA1CA2MAPTCES2CES1 | |
| SCHEMBL2795435 | 0.83 | CYP2C9 (0.55) | CA1CA2MAPTCES2CES1 | |
| SCHEMBL2327512 | 0.83 | CA1 (0.52) | CA1CA2MAPTCES2CES1 | |
| SCHEMBL6404526 | 0.82 | MAPT (0.51) | CA1CA2MAPTCES2CES1 | |
| SCHEMBL1371089 | 0.82 | MAPT (0.51) | CA1CA2MAPTCES2CES1 | |
| SCHEMBL1507665 | 0.81 | CA1 (0.54) | CA1CA2MAPTCES2CES1 | |
| Bromomethane SCHEMBL3169542 | 0.80 | CYP2C9 (0.52) | CA1CA2MAPTCES2CES1 | |
| SCHEMBL1939457 | 0.79 | AKR1C3 (0.54) | CA1CA2MAPTCES2CES1 | |
| SCHEMBL7358417 | 0.79 | MAPT (0.53) | CA1CA2MAPTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273202-A2 | Use of hydroxycarboxylic acids to enhance therapeutic effects of topical compositions for fungal infections and pigmented spots. | Van Scott, Eugene J., Dr. (US) | 1988-07-06 | — | — | EP | claimed |
| EP-1633368-A4 | FOAMABLE PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING A DISORDER | STIEFEL LABORATORIES (US) | 2007-03-14 | — | — | EP | disclosed |
| EP-1633368-A2 | FOAMABLE PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING A DISORDER | STIEFEL LABORATORIES, INC. (US) | 2006-03-15 | — | — | EP | disclosed |
| CN-1182835-C | Towelette product | — | 2005-01-05 | — | — | CN | disclosed |
| WO-2004105702-A2 | FOAMABLE PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING A DISORDER | STIEFEL LABORATORIES, INC. (US) | 2004-12-09 | — | — | WO | disclosed |
| CN-1378442-A | Towlette product | UNILEVER NV (NL) | 2002-11-06 | — | — | CN | disclosed |