Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 7/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | POLB | P06746 | 6/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | PKM | P14618 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | APEX1 | P27695 | 2/20 | 0.68 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.68 |
| ▸ | PTGES | O14684 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 3/20 | 0.67 |
| ▸ | ESR1 | P03372 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.67 |
| ▸ | LCK | P06239 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5145237 | 0.85 | SLC1A3 (1.00) | SLC1A3KMT2APOLBTDP1MEN1 | |
| SCHEMBL5145242 | 0.85 | SLC1A3 (1.00) | SLC1A3KMT2APOLBTDP1MEN1 | |
| SCHEMBL6397420 | 0.85 | SLC1A3 (0.79) | SLC1A3KMT2APOLBTDP1MEN1 | |
| SCHEMBL6397417 | 0.85 | SLC1A3 (0.79) | SLC1A3KMT2APOLBTDP1MEN1 | |
| SCHEMBL29361837 | 0.83 | POLB (0.88) | SLC1A3KMT2APOLBTDP1MEN1 | |
| SCHEMBL14426456 | 0.80 | LCK (1.00) | SLC1A3KMT2APOLBTDP1MEN1 | |
| SCHEMBL6395526 | 0.80 | KMT2A (0.88) | SLC1A3KMT2APOLBTDP1MEN1 | |
| SCHEMBL5145169 | 0.80 | KMT2A (0.88) | SLC1A3KMT2APOLBTDP1MEN1 | |
| SCHEMBL5147456 | 0.79 | SLC1A3 (0.88) | SLC1A3KMT2APOLBTDP1MEN1 | |
| SCHEMBL46577 | 0.79 | SLC1A3 (0.88) | SLC1A3KMT2APOLBTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718308-A4 | METHODS OF MODULATING NEUROTROPHIN-MEDIATED ACTIVITY | PAINCEPTOR PHARMA CORP (CA) | 2007-07-18 | — | — | EP | disclosed |
| EP-1718308-A2 | METHODS OF MODULATING NEUROTROPHIN-MEDIATED ACTIVITY | PainCeptor Pharma Corp. (CA) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005076695-A2 | METHODS OF MODULATING NEUROTROPHIN-MEDIATED ACTIVITY | PAINCEPTOR PHARMA CORPORATION (CA) | 2005-08-25 | — | — | WO | disclosed |