Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 8/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5145281 | 1.00 | KDM4E (0.44) | KDM4ESMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL4314126 | 0.84 | KDM4E (0.45) | KDM4ESMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL4321202 | 0.79 | SMN1; SMN2 (0.41) | KDM4ESMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL4321204 | 0.79 | SMN1; SMN2 (0.41) | KDM4ESMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL5146307 | 0.75 | MAPT (0.46) | KDM4ESMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL4311336 | 0.74 | SMN1; SMN2 (0.45) | KDM4ESMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL5143794 | 0.73 | MCHR1 (0.47) | MCHR1MAPT | |
| SCHEMBL4316016 | 0.73 | SMN1; SMN2 (0.51) | KDM4ESMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL4454170 | 0.70 | SMN1; SMN2 (0.41) | KDM4ESMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL4317648 | 0.68 | KDM4E (0.52) | KDM4ESMN1; SMN2HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748048-A1 | IMIDAZOPYRIDINE COMPOUND | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-01-31 | — | — | EP | disclosed |