Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 19/20 | 0.56 |
| ▸ | CNR2 | P34972 | 16/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5145104 | 0.93 | CNR1 (0.63) | CNR1CNR2 | |
| SCHEMBL5144993 | 0.89 | CNR1 (0.59) | CNR1CNR2TP53GAAMAPT | |
| SCHEMBL5142896 | 0.87 | CNR1 (0.64) | CNR1CNR2 | |
| SCHEMBL5180672 | 0.87 | CNR1 (0.67) | CNR1CNR2 | |
| SCHEMBL5146784 | 0.86 | CNR1 (0.65) | CNR1CNR2 | |
| SCHEMBL5145114 | 0.86 | CNR1 (0.58) | CNR1CNR2 | |
| SCHEMBL5145371 | 0.82 | CNR1 (0.66) | CNR1CNR2 | |
| SCHEMBL5146863 | 0.81 | CNR1 (0.67) | CNR1CNR2 | |
| SCHEMBL5145436 | 0.80 | CNR1 (0.87) | CNR1CNR2 | |
| SCHEMBL14512691 | 0.80 | CNR1 (0.87) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663113-A4 | SUBSTITUTED SULFONAMIDES | MERCK & CO INC (US) | 2007-06-13 | — | — | EP | claimed |
| EP-1663113-A2 | SUBSTITUTED SULFONAMIDES | Merck & Co., Inc. (US) | 2006-06-07 | — | — | EP | claimed |
| WO-2005027837-A2 | SUBSTITUTED SULFONAMIDES | MERCK & CO., INC. (US) | 2005-03-31 | — | — | WO | claimed |