SCHEMBL5145674

SCHEMBL5145674

CS[C](SC)SC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1387260 0.62
SCHEMBL247881 0.59
SCHEMBL7380936 0.59
SCHEMBL3004113 0.59
SCHEMBL50608 0.58
Methylsulfanylmethane SCHEMBL19639841 0.58
SCHEMBL3454770 0.58
Iodide SCHEMBL9413542 0.54
Iodide SCHEMBL2784177 0.54
Hydrochloric Acid SCHEMBL11034699 0.54

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7301029-B2 Bipyridine Derivatives FUJIFILM FINECHEMICALS CO., LTD. (JP) 2007-11-27 US disclosed
US-20060293372-A1 Beta-sheet mimetics and methods relating to the use thereof MYRIAD GENETICS, INC. (US) 2006-12-28 US disclosed
EP-1661566-A2 Use of beta-sheet mimetics as protease and kinase inhibitors and as inhibitors of transcription factors MYRIAD GENETICS, INC. (US) 2006-05-31 EP disclosed
EP-0915700-B1 USE OF BETA-SHEET MIMETICS AS PROTEASE AND KINASE INHIBITORS AND AS INHIBITORS OF TRANSCRIPTION FACTORS MYRIAD GENETICS INC (US) 2006-03-22 EP disclosed
US-20050085642-A1 Novel bipyridine derivatives SANKIO CHEMICAL CO., LTD. 2005-04-21 US disclosed
EP-0933993-A4 SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS BIOCRYST PHARM INC (US) 2004-09-08 EP disclosed
US-20030027819-A1 Beta-sheet mimetics and methods relating to the use thereof MOLECUMETICS LTD. 2003-02-06 US disclosed
EP-1053246-B1 BETA-SHEET MIMETICS AND METHODS RELATING TO THE USE THEREOF MOLECUMETICS LTD (US) 2003-01-02 EP disclosed
US-6372744-B1 PROTEASE OR KINASE INHIBITORS MOLECUMETICS LTD. 2002-04-16 US disclosed
EP-1053246-A1 BETA-SHEET MIMETICS AND METHODS RELATING TO THE USE THEREOF MOLECUMETICS, LTD. (US) 2000-11-22 EP disclosed
US-6117896-A Methods for regulating transcription factors MOLECUMETICS LTD. (US) 2000-09-12 US disclosed
WO-1999041276-A1 β-SHEET MIMETICS AND METHODS RELATING TO THE USE THEREOF MOLECUMETICS LTD. (US) 1999-08-19 WO disclosed
EP-0933993-A1 SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS BIOCRYST PHARMACEUTICALS INC. (US) 1999-08-11 EP disclosed
EP-0915700-A1 USE OF BETA-SHEET MIMETICS AS PROTEASE AND KINASE INHIBITORS AND AS INHIBITORS OF TRANSCRIPTION FACTORS MOLECUMETICS, LTD. (US) 1999-05-19 EP disclosed
WO-1998005333-A1 USE OF BETA-SHEET MIMETICS AS PROTEASE AND KINASE INHIBITORS AND AS INHIBITORS OF TRANSCRIPTION FACTORS MOLECUMETICS LTD. (US) 1998-02-12 WO disclosed
WO-1997047194-A1 SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS BIOCRYST PHARMACEUTICALS, INC. (US) 1997-12-18 WO disclosed
US-4868165-A OSTEOPOROSIS TAISHO PHARMACEUTICAL CO., LTD. (JP) 1989-09-19 US disclosed
EP-0205285-B1 VITAMIN D3 DERIVATIVES TAISHO PHARMACEUTICAL CO. LTD (JP) 1989-08-09 EP disclosed
EP-0205285-A1 Vitamin D3 derivatives TAISHO PHARMACEUTICAL CO. LTD (JP) 1986-12-17 EP disclosed