SCHEMBL5145703

SCHEMBL5145703

C=C(C)C(=O)OC(CC)COC(=O)C=CC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 10/20 0.46
TSHR P16473 4/20 0.38
ALDH1A1 P00352 1/20 0.33
THRB P10828 1/20 0.33
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL195181 1.00 HCAR2 (0.46) HCAR2TSHRALDH1A1THRBATM
SCHEMBL29278356 0.94 TSHR (0.42) HCAR2TSHRALDH1A1THRBATM
SCHEMBL1888381 0.90 TSHR (0.46) HCAR2TSHRTHRB
SCHEMBL15894727 0.88 TSHR (0.45) HCAR2TSHRALDH1A1THRB
SCHEMBL29394650 0.88 TSHR (0.45) HCAR2TSHRALDH1A1THRB
SCHEMBL10168267 0.88 TSHR (0.45) HCAR2TSHRALDH1A1THRB
SCHEMBL7164556 0.83 HCAR2 (0.46) HCAR2TSHRALDH1A1THRBATM
SCHEMBL28397783 0.83 TSHR (0.49) TSHRALDH1A1THRB
SCHEMBL11796011 0.82 TSHR (0.47) HCAR2TSHRALDH1A1THRB
SCHEMBL3914403 0.82 TSHR (0.47) HCAR2TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8349779-B2 Polymers with h-bridge forming functionalities EVONIK ROHMAX ADDITIVES GMBH (DE) 2013-01-08 US claimed
US-8349779-B2 Polymers with h-bridge forming functionalities EVONIK ROHMAX ADDITIVES GMBH (DE) 2013-01-08 US disclosed
US-20070184993-A1 Polymers with h-bridge forming functionalities ROHMAX ADDITIVES GMBH (DE) 2007-08-09 US disclosed
US-6610802-B2 Polymerizing unsatd. monomers with a transition metal catalyst and a coordination compound-forming ligand; filtration using a filter aid having carboxylic acid-, sulfonic acid- or phosphonic acid-containing units ROHMAX ADDITIVES GMBH (DE) 2003-08-26 US disclosed
US-20030060587-A1 Process for synthesis of polymer compositions, polymer compositions obtainable by the process, and use of the same ROHMAX ADDITIVES GMBH (DE) 2003-03-27 US disclosed