SCHEMBL5146335

SCHEMBL5146335

Nc1ncnc2c1ncn2-c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 13/20 1.00
PI4K2B Q8TCG2 13/20 1.00
PI4K2A Q9BTU6 13/20 1.00
PI4KB Q9UBF8 13/20 1.00
EGFR P00533 2/20 1.00
ADORA2A P29274 3/20 0.56
ADORA1 P30542 1/20 0.51
ABL1 P00519 1/20 0.51
CDK1 P06493 1/20 0.51
SRC P12931 1/20 0.51
KDR P35968 1/20 0.51
ABL2 P42684 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenine SCHEMBL9660002 0.87 PI4KA (0.76) PI4KAPI4K2BPI4K2API4KBEGFR
SCHEMBL3538512 0.86 PI4KA (0.77) PI4KAPI4K2BPI4K2API4KBEGFR
Adenine SCHEMBL9660011 0.84 PI4KA (0.71) PI4KAPI4K2BPI4K2API4KBEGFR
SCHEMBL23291064 0.83 PI4KA (0.72) PI4KAPI4K2BPI4K2API4KBEGFR
SCHEMBL21638051 0.83 PI4KA (0.72) PI4KAPI4K2BPI4K2API4KBEGFR
SCHEMBL7249958 0.82 PI4KA (0.72) PI4KAPI4K2BPI4K2API4KBEGFR
SCHEMBL30402719 0.82 PI4KA (0.72) PI4KAPI4K2BPI4K2API4KBEGFR
SCHEMBL25310770 0.81 PI4KA (0.68) PI4KAPI4K2BPI4K2API4KBEGFR
Hydrochloric Acid SCHEMBL8595785 0.81 PI4KA (0.71) PI4KAPI4K2BPI4K2API4KBEGFR
SCHEMBL23869745 0.80 PI4KA (0.71) PI4KAPI4K2BPI4K2API4KBEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101690485-A Preparation for reducing the nitrate content of leafy vegetables NORTHWESTAGRICULTURE AND FORES 2010-04-07 CN claimed
US-5089618-A Converting to N,N'-Bis(trimethylsilyl)derivative; distillation; solvolytic cleavage; hydrolysis; efficiency; high purity LONZA LTD. (CH) 1992-02-18 US claimed
EP-0411467-A2 Process for the preparation of pure adenin LONZA AG (CH) 1991-02-06 EP claimed
JP-3128377-A None JP disclosed
JP-57062279-A None JP disclosed
US-20250359548-A1 METHODS OF IMPROVING STRESS TOLERANCE, GROWTH AND YIELD IN PLANTS VALENT BIOSCIENCES LLC (US) 2025-11-27 US disclosed
US-12402623-B2 Methods of improving stress tolerance, growth and yield in plants VALENT BIOSCIENCES LLC (US) 2025-09-02 US disclosed
US-20240182917-A1 COMPOSITIONS AND METHODS FOR IMPROVING PLASTID TRANSFORMATION EFFICIENCY IN HIGHER PLANTS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2024-06-06 US disclosed
US-20240057597-A1 METHODS OF IMPROVING STRESS TOLERANCE, GROWTH AND YIELD IN PLANTS VALENT BIOSCIENCES LLC (US) 2024-02-22 US disclosed
EP-4120837-B1 INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 2-(3-PHENYLUREIDO)BENZAMIDE, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES UNIV PALACKEHO (CZ) 2024-02-07 EP disclosed
US-11812745-B2 Method of improving stress tolerance, growth and yield in plants VALENT BIOSCIENCES LLC (US) 2023-11-14 US disclosed
US-5419079-A Method of producing virus free potato minitubers TIANJIN RESEARCH INSTITUTE OF VEGATABLE (CN) 1995-05-30 US disclosed
CN-1089076-A Fast propagation technique for potato using depoisoned small seed-potato VEGETABLE INST TIANJIN (CN) 1994-07-13 CN disclosed
US-5089618-A Converting to N,N'-Bis(trimethylsilyl)derivative; distillation; solvolytic cleavage; hydrolysis; efficiency; high purity LONZA LTD. (CH) 1992-02-18 US disclosed
US-5089618-A Converting to N,N'-Bis(trimethylsilyl)derivative; distillation; solvolytic cleavage; hydrolysis; efficiency; high purity LONZA LTD. (CH) 1992-02-18 US disclosed
JP-H03128377-A PURIFICATION OF ADENINE LONZA AG 1991-05-31 JP disclosed
EP-0411467-A2 Process for the preparation of pure adenin LONZA AG (CH) 1991-02-06 EP disclosed
EP-0411467-A2 Process for the preparation of pure adenin LONZA AG (CH) 1991-02-06 EP disclosed
CN-1031637-A A large amount of methods of producing no viroids and viral potato propagation material NOVOTRADE R T (HU) 1989-03-15 CN disclosed
JP-S5762279-A PURIFYING METHOD OF ADENINE KOHJIN CO LTD 1982-04-15 JP disclosed