⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304727 | 0.79 | CA12 (0.46) | — | |
| SCHEMBL304558 | 0.79 | MEN1 (0.33) | — | |
| SCHEMBL2777832 | 0.77 | MEN1 (0.52) | — | |
| SCHEMBL514393 | 0.76 | — | — | |
| SCHEMBL304949 | 0.75 | CA12 (0.50) | — | |
| SCHEMBL514695 | 0.74 | — | — | |
| SCHEMBL2182114 | 0.74 | MEN1 (0.45) | — | |
| SCHEMBL515159 | 0.74 | MEN1 (0.45) | — | |
| SCHEMBL7956546 | 0.74 | CA12 (0.43) | — | |
| SCHEMBL17040541 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132481-A1 | INTERLEUKIN-4 GENE EXPRESSION INHIBITORS | AVENTIS PHARMACEUTICALS INC. | 2008-06-05 | — | — | US | claimed |
| EP-1501797-A1 | 3-SUBSTITUTED AMINO-1H-INDOLE-2-CARBOXYLIC ACID AND 3-SUBSTITUTED AMINO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID DERIVATIVES AS INTERLEUKIN-4 GENE EXPRESSION INHIBITORS | Aventis Pharmaceuticals, Inc. (US) | 2005-02-02 | — | — | EP | claimed |
| US-20040006123-A1 | Interleukin-4 gene expression inhibitors | AVENTIS PHARMACEUTICALS INC. | 2004-01-08 | — | — | US | claimed |
| WO-2003091214-A1 | 3-SUBSTITUTED AMINO-1H-INDOLE-2-CARBOXYLIC ACID AND 3-SUBSTITUTED AMINO-BENZO | AVENTIS PHARMACEUTICALS INC. (US) | 2003-11-06 | — | — | WO | claimed |
| EP-0131793-B1 | 5-AMINOMETHYL-1,3-OXATHIOLANES | BAYER AG (DE) | 1989-01-25 | — | — | EP | claimed |
| US-4615725-A | Tetrahydrofuran-2-ylmethylamines and fungicidal and plant growth regulating use | BAYER AKTIENGESELLSCHAFT (DE) | 1986-10-07 | — | — | US | claimed |
| EP-0158922-A2 | Tetrahydrofuran-2-ylmethylamines | BAYER AG (DE) | 1985-10-23 | — | — | EP | claimed |
| EP-0131793-A2 | 5-Aminomethyl-1,3-oxathiolanes | BAYER AG (DE) | 1985-01-23 | — | — | EP | claimed |
| US-11964957-B2 | Pyrazole derivative and harmful organism-controlling agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2024-04-23 | — | — | US | disclosed |
| EP-3808738-B1 | PYRAZOLE DERIVATIVE AND HARMFUL ORGANISM-CONTROLLING AGENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2024-04-17 | — | — | EP | disclosed |
| CN-112236421-B | Pyrazole derivatives and pest control agents | 组合化学工业株式会社 | 2023-12-26 | — | — | CN | disclosed |
| WO-2023210623-A1 | HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME | 株式会社エス・ディー・エス バイオテック | 2023-11-02 | — | — | WO | disclosed |
| EP-3808738-A1 | PYRAZOLE DERIVATIVE AND HARMFUL ORGANISM-CONTROLLING AGENT | Kumiai Chemical Industry Co., Ltd. (JP) | 2021-04-21 | — | — | EP | disclosed |
| CN-112236421-A | Pyrazole derivative and pest control agent | 组合化学工业株式会社 | 2021-01-15 | — | — | CN | disclosed |
| WO-1988005775-A1 | NOVEL XANTHINE DERIVATIVES | SANDOZ-ERFINDUNGEN VERWALTUNGSGESELLSCHAFT M.B.H. (AT) | 1988-08-11 | — | — | WO | disclosed |
| EP-0254241-A1 | Pyrazolopyridine compounds, their preparation and use | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1988-01-27 | — | — | EP | disclosed |
| US-4615725-A | Tetrahydrofuran-2-ylmethylamines and fungicidal and plant growth regulating use | BAYER AKTIENGESELLSCHAFT (DE) | 1986-10-07 | — | — | US | disclosed |
| EP-0158922-A2 | Tetrahydrofuran-2-ylmethylamines | BAYER AG (DE) | 1985-10-23 | — | — | EP | disclosed |
| US-4542130-A | 5-Aminomethyl-1,3-oxathiolane microbicides, compositions and use | BAYER AKTIENGESELLSCHAFT (DE) | 1985-09-17 | — | — | US | disclosed |
| EP-0131793-A2 | 5-Aminomethyl-1,3-oxathiolanes | BAYER AG (DE) | 1985-01-23 | — | — | EP | disclosed |