Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5674819 | 0.92 | TRPV1 (0.57) | TRPV1EPHX2NR1H4 | |
| SCHEMBL5674452 | 0.83 | EPHX2 (0.54) | TRPV1EPHX2NR1H4 | |
| SCHEMBL5674816 | 0.83 | TRPV1 (0.55) | TRPV1 | |
| SCHEMBL4890952 | 0.81 | TRPV1 (0.50) | TRPV1EPHX2NR1H4 | |
| SCHEMBL4890957 | 0.81 | TRPV1 (0.50) | TRPV1EPHX2NR1H4 | |
| SCHEMBL5313078 | 0.79 | — | — | |
| SCHEMBL5716171 | 0.78 | TRPV1 (0.72) | TRPV1EPHX2NR1H4 | |
| SCHEMBL1268701 | 0.77 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL117355 | 0.77 | NR3C2 (0.67) | TRPV1EPHX2NR1H4 | |
| SCHEMBL5674449 | 0.76 | EPHX2 (0.52) | TRPV1EPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771162-A2 | CAPSAICIN INHIBITORS FOR TREATING OBESITY AND RELATED DISORDERS | NOVO NORDISK A/S (DK) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006007851-A2 | CAPSAICIN INHIBITORS FOR TREATING OBESITY AND-RELATED DISORDERS | NOVO NORDISK A/S (DK) | 2006-01-26 | — | — | WO | disclosed |