Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5147780 | 1.00 | CHRM2 (0.57) | CHRM2CHRM1ADRA1ADRD3ADRA2A | |
| SCHEMBL10098300 | 0.89 | CHRM2 (0.70) | CHRM2CHRM1ADRA1ADRD3ADRA2A | |
| SCHEMBL2166329 | 0.83 | CHRM2 (0.81) | CHRM2CHRM1ADRA1ADRD3ADRA2A | |
| SCHEMBL2166331 | 0.83 | CHRM2 (0.81) | CHRM2CHRM1ADRA1ADRD3ADRA2A | |
| SCHEMBL10098329 | 0.81 | CHRM2 (0.73) | CHRM2CHRM1ADRA1ADRD3ADRA2A | |
| SCHEMBL6761109 | 0.80 | CHRM2 (0.53) | CHRM2CHRM1ADRA1ADRD3ADRA2A | |
| SCHEMBL6757054 | 0.79 | CHRM2 (0.52) | CHRM2CHRM1ADRA1ADRD3ADRA2A | |
| SCHEMBL10098303 | 0.78 | CHRM2 (0.69) | CHRM2CHRM1ADRA1ADRD3ADRA2A | |
| SCHEMBL723472 | 0.78 | CHRM2 (0.82) | CHRM2CHRM1ADRA1ADRD3ADRA2A | |
| SCHEMBL723471 | 0.78 | CHRM2 (0.82) | CHRM2CHRM1ADRA1ADRD3ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7230030-B2 | Derivatives of 3,3-diphenylpropylamines | SCHWARZ PHARMA AG (DE) | 2007-06-12 | — | — | US | disclosed |