Congo Red Free Acid

Congo Red Free Acid

SCHEMBL5147845

Nc1c(/N=N/c2ccc(-c3ccc(/N=N/c4cc(S(=O)(=O)O)c5ccccc5c4N)cc3)cc2)cc(S(=O)(=O)O)c2ccccc12.[NaH].[NaH]

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.97
ALDH1A1 P00352 2/20 0.97
THRB P10828 2/20 0.97
HPGD P15428 2/20 0.97
ALOX12 P18054 2/20 0.97
RECQL P46063 2/20 0.97
MEN1 O00255 1/20 0.97
MAPT P10636 1/20 0.97
SNCA P37840 1/20 0.97
BLM P54132 1/20 0.97
KMT2A Q03164 1/20 0.97
TDP1 Q9NUW8 1/20 0.97
SENP2 Q9HC62 4/20 0.82
SENP1 Q9P0U3 4/20 0.82
SUMO2 P61956 3/20 0.82
SUMO1 P63165 3/20 0.82
SENP7 Q9BQF6 3/20 0.82
SLC7A11 Q9UPY5 5/20 0.77
ENPP2 Q13822 3/20 0.72
GLB1 P16278 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Congo Red Free Acid SCHEMBL17272057 1.00 APP (0.97) APPALDH1A1THRBHPGDALOX12
Congo Red Free Acid SCHEMBL326268 1.00 APP (0.97) APPALDH1A1THRBHPGDALOX12
Congo Red Free Acid SCHEMBL2583894 0.99 APP (1.00) APPALDH1A1THRBHPGDALOX12
Congo Red Free Acid SCHEMBL29825625 0.99 APP (1.00) APPALDH1A1THRBHPGDALOX12
Congo Red Free Acid SCHEMBL29350758 0.99 APP (1.00) APPALDH1A1THRBHPGDALOX12
Congo Red Free Acid SCHEMBL1254806 0.99 APP (1.00) APPALDH1A1THRBHPGDALOX12
Congo Red Free Acid SCHEMBL29415044 0.97 APP (0.97) APPALDH1A1THRBHPGDALOX12
SCHEMBL14988501 0.94 APP (0.86) APPALDH1A1THRBHPGDALOX12
SCHEMBL14988498 0.94 APP (0.86) APPALDH1A1THRBHPGDALOX12
SCHEMBL18044243 0.92 APP (0.88) APPALDH1A1THRBHPGDALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247670-B2 Semi-conducting carbon nanotube GENERAL ELECTRIC COMPANY (US) 2007-07-24 US claimed
US-20030219377-A1 Compounds and methods for diagnosing and treating amyloid-related conditions PHARMACIA & UPJOHN COMPANY 2003-11-27 US disclosed
US-6589504-B1 Binding or aggregating fibrils with radiolabeled quinoline-hydrazone compound PHARMACIA & UPJOHN COMPANY 2003-07-08 US disclosed
US-4764302-A Thickening system for incorporating fluorescent whitening agents THE CLOROX COMPANY (US) 1988-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030219377-A1 Compounds and methods for diagnosing and treating amyloid-related conditions APP, IAPP, HTT APP 1/4885ALDH1A1 694/4885THRB 4735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.