Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 5/20 | 0.43 |
| ▸ | MMP9 | P14780 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457886 | 0.92 | MME (0.53) | MMENPSR1NAALAD2MMP2MMP9 | |
| SCHEMBL457887 | 0.92 | MME (0.53) | MMENPSR1NAALAD2MMP2MMP9 | |
| SCHEMBL93439 | 0.87 | GNPAT (0.58) | GNPATMMENPSR1ALPIPKM | |
| SCHEMBL5694618 | 0.87 | GNPAT (0.58) | GNPATMMENPSR1ALPIPKM | |
| SCHEMBL412958 | 0.87 | GNPAT (0.58) | GNPATMMENPSR1ALPIPKM | |
| SCHEMBL93440 | 0.87 | GNPAT (0.58) | GNPATMMENPSR1ALPIPKM | |
| Hydrochloric Acid SCHEMBL27197703 | 0.85 | GNPAT (0.57) | GNPATMMENPSR1ALPIPKM | |
| Oxalic Acid SCHEMBL8649953 | 0.84 | GNPAT (0.56) | GNPATMMENPSR1ALPIPKM | |
| Malonic Acid SCHEMBL8644619 | 0.82 | GNPAT (0.55) | GNPATMMENPSR1ALPIPKM | |
| Succinic Acid SCHEMBL8643183 | 0.81 | NAALAD2 (0.60) | GNPATMMENPSR1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1755584-A4 | TREATMENT OF MYOPIA | UNIV CALIFORNIA (US) | 2007-10-31 | — | — | EP | disclosed |
| EP-1755584-A1 | TREATMENT OF MYOPIA | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005110397-A1 | TREATMENT OF MYOPIA | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-11-24 | — | — | WO | disclosed |