Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 20/20 | 0.62 |
| ▸ | CNR2 | P34972 | 7/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2653109 | 0.94 | CNR1 (0.62) | CNR1CNR2CYP2D6CYP2C9KCNH2 | |
| SCHEMBL3668309 | 0.93 | CNR1 (0.72) | CNR1CNR2CYP2D6CYP2C9KCNH2 | |
| SCHEMBL1567733 | 0.93 | CNR1 (0.72) | CNR1CNR2CYP2D6CYP2C9KCNH2 | |
| SCHEMBL2170495 | 0.93 | CNR1 (0.72) | CNR1CNR2CYP2D6CYP2C9KCNH2 | |
| SCHEMBL2653521 | 0.92 | CNR1 (0.63) | CNR1CNR2CYP2D6CYP2C9KCNH2 | |
| SCHEMBL5153055 | 0.91 | CNR1 (0.63) | CNR1CNR2CYP2D6CYP2C9KCNH2 | |
| SCHEMBL5150514 | 0.90 | CNR1 (0.58) | CNR1CNR2CYP2D6CYP2C9KCNH2 | |
| SCHEMBL5185117 | 0.89 | CNR1 (0.60) | CNR1CNR2CYP2D6CYP2C9KCNH2 | |
| SCHEMBL4692401 | 0.86 | CNR1 (0.68) | CNR1CNR2CYP2D6CYP2C9KCNH2 | |
| SCHEMBL4691414 | 0.86 | CNR1 (0.62) | CNR1CNR2CYP2D6CYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641493-A4 | RADIOLABELED CANNABINOID-1 RECEPTOR MODULATORS | MERCK & CO INC (US) | 2007-10-31 | — | — | EP | claimed |
| EP-1641493-A1 | RADIOLABELED CANNABINOID-1 RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2006-04-05 | — | — | EP | claimed |
| WO-2005009479-A1 | RADIOLABELED CANNABINOID-1 RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2005-02-03 | — | — | WO | claimed |
| EP-1641493-A4 | RADIOLABELED CANNABINOID-1 RECEPTOR MODULATORS | MERCK & CO INC (US) | 2007-10-31 | — | — | EP | disclosed |
| EP-1641493-A1 | RADIOLABELED CANNABINOID-1 RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2006-04-05 | — | — | EP | disclosed |
| WO-2005009479-A1 | RADIOLABELED CANNABINOID-1 RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2005-02-03 | — | — | WO | disclosed |