Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272663 | 0.88 | CYP3A4 (0.88) | CYP3A4 | |
| SCHEMBL272237 | 0.81 | CYP3A4 (0.76) | CYP3A4 | |
| SCHEMBL272662 | 0.79 | CYP3A4 (0.73) | CYP3A4 | |
| SCHEMBL2974491 | 0.78 | CYP3A4 (0.71) | CYP3A4 | |
| SCHEMBL271125 | 0.78 | CYP3A4 (0.84) | CYP3A4 | |
| SCHEMBL271852 | 0.78 | CYP3A4 (0.84) | CYP3A4 | |
| SCHEMBL271851 | 0.78 | CYP3A4 (0.84) | CYP3A4 | |
| SCHEMBL273373 | 0.77 | CYP3A4 (0.70) | CYP3A4 | |
| SCHEMBL273372 | 0.77 | CYP3A4 (0.70) | CYP3A4 | |
| SCHEMBL272244 | 0.77 | CYP3A4 (0.67) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1993820-A2 | NOVEL COMPOUNDS THAT ARE USEFUL FOR IMPROVING PHARMACOKINETICS | Abbott Laboratories (US) | 2008-11-26 | — | — | EP | claimed |
| WO-2007103670-A2 | NOVEL COMPOUNDS THAT ARE USEFUL FOR IMPROVING PHARMACOKINETICS | ABBOTT LABORATORIES (US) | 2007-09-13 | — | — | WO | claimed |