Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28742280 | 1.00 | EGFR (0.52) | EGFRALDH1A1KDM4EMAPTRPS6KA5 | |
| SCHEMBL29367065 | 1.00 | EGFR (0.52) | EGFRALDH1A1KDM4EMAPTRPS6KA5 | |
| Hydrochloric Acid SCHEMBL22289522 | 0.98 | EGFR (0.50) | EGFRALDH1A1KDM4EMAPTRPS6KA5 | |
| Hydrochloric Acid SCHEMBL30980980 | 0.98 | EGFR (0.50) | EGFRALDH1A1KDM4EMAPTRPS6KA5 | |
| SCHEMBL29188217 | 0.98 | EGFR (0.50) | EGFRALDH1A1KDM4EMAPTRPS6KA5 | |
| Pyrimidine SCHEMBL28750071 | 0.94 | EGFR (0.47) | EGFRALDH1A1KDM4EMAPTRPS6KA5 | |
| Pyridine SCHEMBL27558287 | 0.92 | EGFR (0.45) | EGFRALDH1A1KDM4EMAPTRPS6KA5 | |
| Pyrrole SCHEMBL82535 | 0.88 | EGFR (0.42) | EGFRALDH1A1KDM4EMAPTRPS6KA5 | |
| SCHEMBL29048833 | 0.83 | EGFR (0.41) | EGFRALDH1A1KDM4EMAPTRPS6KA5 | |
| SCHEMBL1533934 | 0.82 | EGFR (0.55) | EGFRALDH1A1RPS6KA5CYP2A6PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 11845 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120699015-B | Pyridopyrimidine compound containing morpholine structure, and preparation method and application thereof | 江西科技师范大学 | 2026-05-12 | — | — | CN | claimed |
| US-12595297-B2 | Methods and compositions for inhibition of EGF/EGFR pathway in combination with tyrosine kinase inhibitors | IN3BIO LTD. (BM) | 2026-04-07 | — | — | US | claimed |
| EP-4396191-B1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2026-02-18 | — | — | EP | claimed |
| US-12523648-B1 | Fluorescent indicators for calcium metal ion detection | ION Biosciences (US) | 2026-01-13 | — | — | US | claimed |
| US-20250381243-A1 | HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC (US) | 2025-12-18 | — | — | US | claimed |
| WO-2025240673-A1 | CANCER TREATMENT USING AKT INHIBITORS AND PLK1 INHIBITORS | CARDIFF ONCOLOGY, INC. (US) | 2025-11-20 | — | — | WO | claimed |
| US-20250354111-A1 | BOVINE SEX-SORTED SPERM SORTING SOLUTION MEDIATED BY SMALL MOLECULE COMPOUND AND ITS APPLICATION | INNER MONGOLIA UNIVERSITY (CN) | 2025-11-20 | — | — | US | claimed |
| US-12439820-B2 | Organic electroluminescence device and amine compound for organic electroluminescence device | SAMSUNG DISPLAY CO., LTD. (KR) | 2025-10-07 | — | — | US | claimed |
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | claimed |
| CN-120202002-A | Pharmaceutical composition for treating cancer | 微境生物医药科技(上海)有限公司 | 2025-06-24 | — | — | CN | claimed |
| EP-0021292-B1 | ALKOXYBENZYLPYRIDOPYRIMIDINES, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS THEREOF | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-03-09 | — | — | EP | claimed |
| US-4368198-A | BACTERICIDES ESPECIALLY ANTI-PSEUDOMONAS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1983-01-11 | — | — | US | claimed |
| US-4302454-A | Cephalosporins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-11-24 | — | — | US | claimed |
| EP-0021292-A1 | Alkoxybenzylpyridopyrimidines, methods for their preparation and pharmaceutical formulations thereof | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-01-07 | — | — | EP | claimed |
| US-4226863-A | BACTERICIDES, ANTIBIOTICS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-10-07 | — | — | US | claimed |
| US-4165373-A | ANTIBIOTICS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-08-21 | — | — | US | claimed |
| US-4160087-A | BACTERICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-07-03 | — | — | US | claimed |
| US-4156724-A | N-acylamino-alpha-arylacetamido cephalosporins and antibacterial compositions and methods containing them | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-05-29 | — | — | US | claimed |
| US-4125611-A | MICROBIOCIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1978-11-14 | — | — | US | claimed |
| US-4005075-A | Penicillins and their preparation | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-01-25 | — | — | US | claimed |