SCHEMBL5149283

SCHEMBL5149283

CCC[C@H](NS(=O)(=O)c1cccc2c(N(C)C)cccc12)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.52
F2 P00734 1/20 0.52
EDNRA P25101 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9751607 1.00 TYMS (0.52) TYMSF2EDNRA
SCHEMBL1168294 0.93
SCHEMBL1168296 0.93
SCHEMBL10963011 0.93
SCHEMBL29632046 0.93
SCHEMBL16179325 0.91 GLB1 (0.52)
SCHEMBL5052275 0.91 GLB1 (0.52)
SCHEMBL5706271 0.90 TYMS (0.54) TYMSF2EDNRA
SCHEMBL3863361 0.89 HDAC4 (0.53) TYMSF2EDNRA
SCHEMBL3863358 0.89 HDAC4 (0.53) TYMSF2EDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024136755-A1 ALBUMIN BINDING COMPOUNDS AND METHODS OF USE THEREOF NATIONAL UNIVERSITY OF SINGAPORE (SG) 2024-06-27 WO disclosed
CN-103464125-B Preparation method and application of novel triazole bridging compound cyclodextrin chiral stationary phase UNIV TIANJIN 2014-12-24 CN disclosed
CN-103464125-A Preparation method and application of novel triazole bridging compound cyclodextrin chiral stationary phase UNIV TIANJIN 2013-12-25 CN disclosed
US-20070225490-A1 Cationic Oligomer of a Saccharide for Resolving Enantiomers and Asymmetric Synthesis SELEX SENSORS AND AIRBORNE SYSTEMS LIMITED (GB) 2007-09-27 US disclosed
WO-2005056609-A1 CATIONIC OLIGOMER OF A SACCHARIDE FOR RESOLVING ENANTIOMERS AND ASYMMETRIC SYNTHESIS NATIONAL UNIVERSITY OF SINGAPORE (SG) 2005-06-23 WO disclosed
US-5066785-A CARBOXYL TERMINAL PEPTIDE AND PROTEIN SEQUENCING CITY OF HOPE (US) 1991-11-19 US disclosed
EP-0407527-A4 CARBOXYL TERMINAL PEPTIDE AND PROTEIN SEQUENCING 1991-10-30 EP disclosed
EP-0407527-A1 CARBOXYL TERMINAL PEPTIDE AND PROTEIN SEQUENCING CITY OF HOPE (US) 1991-01-16 EP disclosed
US-4935494-A C-terminal peptide and protein sequencing CITY OF HOPE (US) 1990-06-19 US disclosed
WO-1990005739-A1 CARBOXYL TERMINAL PEPTIDE AND PROTEIN SEQUENCING MILLER CHAD G (US) 1990-05-31 WO disclosed