Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL5146756 | 0.97 | KMT2A (0.47) | KMT2AMEN1NPSR1PABPC1ATM | |
| Hydrochloric Acid SCHEMBL5146805 | 0.97 | KMT2A (0.47) | KMT2AMEN1NPSR1PABPC1ATM | |
| Bromide SCHEMBL5150406 | 0.85 | NPSR1 (0.55) | KMT2AMEN1NPSR1ATML3MBTL1 | |
| Fluoride Ion SCHEMBL5148030 | 0.82 | NPSR1 (0.55) | KMT2AMEN1NPSR1ATML3MBTL1 | |
| Hydrochloric Acid SCHEMBL2810527 | 0.82 | NPSR1 (0.55) | KMT2AMEN1NPSR1ATML3MBTL1 | |
| Bromide SCHEMBL17906576 | 0.81 | KMT2A (0.52) | KMT2AMEN1NPSR1PABPC1ATM | |
| Bromide SCHEMBL29902123 | 0.81 | KMT2A (0.52) | KMT2AMEN1NPSR1PABPC1ATM | |
| SCHEMBL9811331 | 0.75 | KMT2A (0.53) | KMT2AMEN1NPSR1PABPC1ATM | |
| SCHEMBL10307407 | 0.75 | KMT2A (0.53) | KMT2AMEN1NPSR1PABPC1ATM | |
| Bromide SCHEMBL5146792 | 0.75 | NPSR1 (0.71) | KMT2AMEN1NPSR1PABPC1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1870495-A1 | Aqueous alkaline, cyanide-free, bath for the galvanic deposition of Zinc and Zinc alloy layers | ATOTECH DEUTSCHLAND GMBH (DE) | 2007-12-26 | — | — | EP | disclosed |