Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 9/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.46 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5153089 | 1.00 | SLC22A1 (0.50) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL5150584 | 1.00 | SLC22A1 (0.50) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL5150286 | 0.95 | SLC22A1 (0.46) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL5150677 | 0.95 | SLC22A1 (0.46) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL5150559 | 0.95 | SLC22A1 (0.46) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL2861267 | 0.80 | SLC22A1 (0.50) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL16936119 | 0.80 | SLC22A1 (0.50) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL16936160 | 0.80 | SLC22A1 (0.50) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL28687608 | 0.78 | SLC22A1 (0.48) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL29120975 | 0.78 | SLC22A1 (0.48) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689698-A4 | BIS-CATIONIC COMPOUNDS AND USE THEREOF | UNIV SYDNEY (AU) | 2007-09-05 | — | — | EP | claimed |
| JP-2007510672-A | — | — | 2007-04-26 | — | — | JP | claimed |
| EP-1689698-A1 | BIS-CATIONIC COMPOUNDS AND USE THEREOF | THE UNIVERSITY OF SYDNEY (AU) | 2006-08-16 | — | — | EP | claimed |
| WO-2005047230-A1 | BIS-CATIONIC COMPOUNDS AND USE THEREOF | THE UNIVERSITY OF SYDNEY (AU) | 2005-05-26 | — | — | WO | claimed |
| EP-1689698-A4 | BIS-CATIONIC COMPOUNDS AND USE THEREOF | UNIV SYDNEY (AU) | 2007-09-05 | — | — | EP | disclosed |
| EP-1689698-A1 | BIS-CATIONIC COMPOUNDS AND USE THEREOF | THE UNIVERSITY OF SYDNEY (AU) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005047230-A1 | BIS-CATIONIC COMPOUNDS AND USE THEREOF | THE UNIVERSITY OF SYDNEY (AU) | 2005-05-26 | — | — | WO | disclosed |