Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7429002 | 0.98 | NPC1 (0.32) | NPC1RAB9ANOTUM | |
| SCHEMBL2854030 | 0.86 | NOTUM (0.32) | NOTUM | |
| SCHEMBL148063 | 0.84 | — | — | |
| Water SCHEMBL29953274 | 0.82 | NOTUM (0.39) | NPC1RAB9ANOTUM | |
| Bromide SCHEMBL27914400 | 0.82 | SMN1; SMN2 (0.35) | NPC1RAB9ANOTUM | |
| SCHEMBL19603001 | 0.80 | — | — | |
| Zinc Ion SCHEMBL14482007 | 0.80 | — | — | |
| SCHEMBL8080946 | 0.80 | KMT2A (0.33) | — | |
| SCHEMBL8490277 | 0.80 | S1PR2 (0.38) | NPC1RAB9ANOTUM | |
| SCHEMBL20571366 | 0.79 | CREBBP (0.39) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1390340-A4 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INST TECHNOLOGY (US) | 2007-07-25 | — | — | EP | disclosed |
| EP-0988290-B1 | CARBONYLDIIMIDAZOLES, THEIR ESTER DERIVATIVES AND METHOD FOR THEIR PRODUCTION | BASF AG (DE) | 2007-01-10 | — | — | EP | disclosed |
| EP-1390340-A1 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002085838-A1 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2002-10-31 | — | — | WO | disclosed |
| US-6410744-B1 | REACTING AN IMIDAZOLE COMPOUND WITH PHOSGENE IN A SOLVENT | BASF AKTIENGESELLSCHAFT (DE) | 2002-06-25 | — | — | US | disclosed |
| EP-0988290-A1 | CARBONYLDIIMIDAZOLES, THEIR ESTER DERIVATIVES AND METHOD FOR THEIR PRODUCTION | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998056769-A1 | CARBONYLDIIMIDAZOLES, THEIR ESTER DERIVATIVES AND METHOD FOR THEIR PRODUCTION | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-17 | — | — | WO | disclosed |