Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 2/20 | 0.52 |
| ▸ | CCND1 | P24385 | 2/20 | 0.52 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.52 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.52 |
| ▸ | ITGAL | P20701 | 3/20 | 0.52 |
| ▸ | SNCA | P37840 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | ICMT | O60725 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.45 |
| ▸ | CCKBR | P32239 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5149333 | 0.83 | CDK4 (0.53) | CDK4CCND1ITGB2ICAM1ITGAL | |
| SCHEMBL4601988 | 0.82 | CDK4 (0.57) | CDK4CCND1ITGB2ICAM1ITGAL | |
| SCHEMBL14557962 | 0.82 | ITGB2 (0.45) | ITGB2ICAM1ITGALSNCAICMT | |
| SCHEMBL5152497 | 0.79 | HDAC3 (0.51) | CDK4CCND1ITGB2ICAM1ITGAL | |
| SCHEMBL13902824 | 0.79 | MEN1 (0.61) | ITGB2ICAM1ITGALTSHRERAP2 | |
| SCHEMBL5149376 | 0.79 | CDK4 (0.53) | CDK4CCND1ITGB2ICAM1ITGAL | |
| SCHEMBL14557959 | 0.79 | PPARG (0.42) | ITGB2ICAM1ITGALSNCAANO1 | |
| SCHEMBL14557932 | 0.78 | SCN9A (0.41) | ITGB2ICAM1ITGALSNCATSHR | |
| SCHEMBL4601301 | 0.78 | KMT2A (0.58) | CDK4CCND1HPGDSERAP2HDAC3 | |
| SCHEMBL5152158 | 0.78 | KMT2A (0.58) | CDK4CCND1HPGDSERAP2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | FSHR, NPY1R, NPY2R | CDK4 4400/4885CCND1 592/4885ITGB2 4080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.