Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | IGF1R | P08069 | 7/20 | 0.39 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13662800 | 1.00 | HRH3 (0.44) | HRH3CYP2C19IGF1RHMOX1MEN1 | |
| SCHEMBL15184685 | 1.00 | HRH3 (0.44) | HRH3CYP2C19IGF1RHMOX1MEN1 | |
| Acetic Acid SCHEMBL28854263 | 0.89 | CYP1A2 (0.44) | HRH3CYP2C19IGF1RMEN1KMT2A | |
| SCHEMBL10457217 | 0.83 | TAAR1 (0.54) | HRH3CYP2C19CYP1A2 | |
| SCHEMBL2690630 | 0.82 | CYP2C19 (0.40) | CYP2C19IGF1RHMOX1MEN1KMT2A | |
| SCHEMBL15184752 | 0.81 | AOC3 (0.47) | HRH3CYP2C19 | |
| SCHEMBL867450 | 0.81 | AOC3 (0.47) | HRH3CYP2C19 | |
| SCHEMBL21353855 | 0.81 | AOC3 (0.47) | HRH3CYP2C19IGF1RMEN1KMT2A | |
| SCHEMBL7104502 | 0.81 | AOC3 (0.47) | HRH3CYP2C19IGF1RMEN1KMT2A | |
| SCHEMBL3245046 | 0.81 | HRH3 (0.43) | HRH3CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486836-A | Preparation method of 2-aryl-3-carbonyl substituted tetrahydrofuran and tetrahydropyran compound | 遵义医科大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-104450852-B | A kind of preparation method of homoallylic alcohol class compound | 宁夏大学 | 2018-01-09 | — | — | CN | disclosed |
| CN-104478936-B | The preparation and application of bi triphenyl antimony organic (V) title complex of a kind of ionic | 湖南大学 | 2016-06-08 | — | — | CN | disclosed |
| CN-104478936-A | Preparation method and application of ionic type bis-triphenyl organic antimony (V) complex | UNIV HUNAN | 2015-04-01 | — | — | CN | disclosed |
| CN-104450852-A | Method for preparing homoallylic alcohol compound | UNIV NINGXIA | 2015-03-25 | — | — | CN | disclosed |
| US-7314943-B2 | Pyran derivatives containing an exocyclic double bond | MERCK PATENT GMBH (DE) | 2008-01-01 | — | — | US | disclosed |
| US-7314943-B2 | Pyran derivatives containing an exocyclic double bond | MERCK PATENT GMBH (DE) | 2008-01-01 | — | — | US | disclosed |
| EP-1515945-A4 | METHOD FOR MAKING ARYL HYDRAZINES AND SUBSTITUTED INDOLES | RHODIA PHARMA SOLUTION INC FOR (US) | 2007-07-18 | — | — | EP | disclosed |
| EP-1515945-A2 | METHOD FOR MAKING ARYL HYDRAZINES AND SUBSTITUTED INDOLES | Rhodia Pharma Solution Inc., (formally Rhodia Chirex Inc.) (US) | 2005-03-23 | — | — | EP | disclosed |
| WO-2004000218-A2 | METHOD FOR MAKING ARYL HYDRAZINES AND SUBSTITUTED INDOLES | RHODIA PHARMA SOLUTIONS INC., (FORMALLY RHODIA CHIREX INC.) (US) | 2003-12-31 | — | — | WO | disclosed |
| US-6489512-B1 | REACTING AROMATIC COMPOUND BEARING ACTIVATED CARBON ATOM AND HYDRAZONE IN PRESENCE OF TRANSITION METAL CATALYST TO FORM ARYL HYDRAZONE, HYDROLYZING TO FORM ARYL HYDRAZINE, CYCLIZING IN PRESENCE OF ACID CATALYST TO FORM SUBSTITUTED INDOLE | RHODIA CHIREX INC. | 2002-12-03 | — | — | US | disclosed |