Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 14/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.48 |
| ▸ | CASP1 | P29466 | 11/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.48 |
| ▸ | CASP7 | P55210 | 10/20 | 0.48 |
| ▸ | USP2 | O75604 | 9/20 | 0.48 |
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | VNN1 | O95497 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8241057 | 0.88 | CYP1A2 (0.42) | CYP1A2ALDH1A1CASP1CYP3A4CASP7 | |
| SCHEMBL14407605 | 0.86 | CYP1A2 (0.50) | CYP1A2ALDH1A1CASP1CYP3A4CASP7 | |
| SCHEMBL5175702 | 0.86 | CYP1A2 (0.51) | CYP1A2ALDH1A1CASP1CYP3A4CASP7 | |
| SCHEMBL5157503 | 0.84 | CYP1A2 (0.52) | CYP1A2ALDH1A1CASP1CYP3A4CASP7 | |
| SCHEMBL5155796 | 0.82 | CYP1A2 (0.49) | CYP1A2ALDH1A1CASP1CYP3A4CASP7 | |
| SCHEMBL5154014 | 0.82 | CYP1A2 (0.54) | CYP1A2ALDH1A1CASP1CYP3A4CASP7 | |
| SCHEMBL5152081 | 0.81 | CYP1A2 (0.50) | CYP1A2ALDH1A1CASP1CYP3A4CASP7 | |
| SCHEMBL5336597 | 0.81 | CYP1A2 (0.48) | CYP1A2ALDH1A1CASP1CYP3A4CASP7 | |
| SCHEMBL5153441 | 0.80 | CYP1A2 (0.53) | CYP1A2ALDH1A1CASP1CYP3A4CASP7 | |
| SCHEMBL5153425 | 0.80 | CYP1A2 (0.53) | CYP1A2ALDH1A1CASP1CYP3A4CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225304-A1 | AMINOPURINE DERIVATIVES FOR TREATING NEURODEGENERATIVE DISEASES | PHARMACOPEIA DRUG DISCOVERY, INC. (US) | 2007-09-27 | — | — | US | disclosed |
| US-20070225304-A1 | AMINOPURINE DERIVATIVES FOR TREATING NEURODEGENERATIVE DISEASES | PHARMACOPEIA DRUG DISCOVERY, INC. (US) | 2007-09-27 | — | — | US | disclosed |
| US-20070225304-A1 | AMINOPURINE DERIVATIVES FOR TREATING NEURODEGENERATIVE DISEASES | PHARMACOPEIA DRUG DISCOVERY, INC. (US) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225304-A1 | AMINOPURINE DERIVATIVES FOR TREATING NEURODEGENERATIVE DISEASES | TPMT, ADORA2A, ENTPD5 | CYP1A2 1457/4885ALDH1A1 705/4885CASP1 628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.