SCHEMBL5153485

SCHEMBL5153485

Cc1ccc(S(=O)(=O)c2cc(O)c(O)c(O)c2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.64
COMT P21964 2/20 0.56
RAPGEF4 Q8WZA2 2/20 0.50
CA2 P00918 3/20 0.49
PKM P14618 1/20 0.49
MEN1 O00255 2/20 0.48
ALDH1A1 P00352 2/20 0.48
MAPT P10636 2/20 0.48
KMT2A Q03164 2/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA3 P07451 1/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA5B Q9Y2D0 1/20 0.48
SNCA P37840 1/20 0.47
HTT P42858 3/20 0.46
USP2 O75604 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5153996 0.86 GAA (0.52) GAACOMTRAPGEF4CA2PKM
SCHEMBL4869370 0.85 GAA (0.50) GAACOMTPKMALDH1A1KMT2A
SCHEMBL312194 0.84 GAA (0.64) GAACOMTRAPGEF4CA2PKM
SCHEMBL12409037 0.83 GAA (0.84) GAACOMTRAPGEF4CA2PKM
SCHEMBL6847517 0.82 COMT (0.49) GAACOMTMEN1ALDH1A1MAPT
SCHEMBL5153377 0.82 GAA (0.47) GAACOMTRAPGEF4CA2PKM
SCHEMBL4861734 0.81 GAA (0.46) GAACOMTCA2PKMMEN1
SCHEMBL5150340 0.80 COMT (0.47) GAACOMTRAPGEF4CA2PKM
SCHEMBL4400955 0.80 GAA (1.00) GAARAPGEF4CA2PKMMEN1
SCHEMBL10067072 0.80 GAA (1.00) GAARAPGEF4CA2PKMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1245403-B1 Thermographic recording material with improved image tone. AGFA GEVAERT (BE) 2007-01-03 EP disclosed
US-7153635-B1 Thermally developable materials processable at lower temperatures EASTMAN KODAK COMPANY (US) 2006-12-26 US disclosed
US-20060093974-A1 Thermally developable materials processable at lower temperatures EASTMAN KODAK COMPANY 2006-05-04 US disclosed
US-20060019205-A1 Thermographic materials processable at lower temperatures EASTMAN KODAK COMPANY 2006-01-26 US disclosed
US-20050186521-A1 Black-and-white thermographic materials with improved image tone EASTMAN KODAK COMPANY 2005-08-25 US disclosed
US-6774084-B2 BLACK AND WHITE LIGHT-INSENSITIVE THERMOGRAPHIC RECORDING MEDIA COMPRISING A THERMOSENSITIVE ELEMENT HAVING ORGANIC SILVER SALT, A 1,2-DIHYDROXYBENZENE CONTAINING AN ESTER OR SULFOXIDE GROUP AND BINDER; COVERING POWER; STORAGE STABILITY AGFA-GEVAERT (BE) 2004-08-10 US disclosed
US-6693062-B2 LIGHT INSENSITIVE ORGANIC SILVER SALTS, REDUCING AGENTS AND 1,2-DIHYDROXYBENZENE DERIVATIVE AGFA-GEVAERT (BE) 2004-02-17 US disclosed
US-20030186809-A1 Thermographic recording material with improved image tone AGFA-GEVAERT (BE) 2003-10-02 US disclosed
EP-1270255-A1 Thermographic recording material with improved image tone Agfa-Gevaert (BE) 2003-01-02 EP disclosed