Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10501335 | 0.98 | ATM (0.40) | ATMEGFRHSP90AA1IDO1CDK2 | |
| SCHEMBL7657126 | 0.78 | CYP2A6 (0.32) | — | |
| SCHEMBL14999437 | 0.74 | EGFR (0.34) | ATMEGFRRAB9A | |
| SCHEMBL28675792 | 0.74 | EGFR (0.34) | ATMEGFRHSP90AA1 | |
| SCHEMBL31216375 | 0.72 | CYP1A2 (0.38) | — | |
| SCHEMBL8541719 | 0.72 | CYP1A2 (0.38) | — | |
| SCHEMBL1785837 | 0.72 | MEN1 (0.40) | — | |
| SCHEMBL3854510 | 0.71 | KDM4E (0.37) | ATM | |
| SCHEMBL253244 | 0.70 | ATM (0.41) | ATMNPC1RAB9A | |
| SCHEMBL7057830 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 434 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113321642-A | Quinazoline imine compound and application and preparation method thereof | 北京鑫开元医药科技有限公司 | 2021-08-31 | — | — | CN | claimed |
| EP-3018206-B1 | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES | NUEVOLUTION AS (DK) | 2021-08-11 | — | — | EP | claimed |
| CN-104151255-B | A kind of polysubstituted quinazoline imine derivative and preparation method thereof | 清华大学 | 2016-07-13 | — | — | CN | claimed |
| CN-104151255-A | Polysubstituted quinazoline imine derivative and preparation method thereof | UNIV TSINGHUA | 2014-11-19 | — | — | CN | claimed |
| US-8569350-B2 | Anti-mitotic anti-proliferative compounds | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2013-10-29 | — | — | US | claimed |
| US-20120149744-A1 | ANTI-MITOTIC ANTI-PROLIFERATIVE COMPOUNDS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2012-06-14 | — | — | US | claimed |
| US-8143299-B2 | Anti-mitotic anti-proliferative compounds | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2012-03-27 | — | — | US | claimed |
| EP-1673663-B1 | LIGHT SENSITIVE COATING COMPOSITIONS FOR LITHOGRAPHIC ELEMENTS | IBF IND BRASILEIRA DE FILMES SA (BR) | 2011-03-23 | — | — | EP | claimed |
| US-20090317440-A1 | ANTI-MITOTIC ANTI-PROLIFERATIVE COMPOUNDS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2009-12-24 | — | — | US | claimed |
| EP-1817028-A2 | ANTI-MITOTIC ANTI-PROLIFERATIVE COMPOUNDS | University of Medicine and Dentistry of New Jersey (US) | 2007-08-15 | — | — | EP | claimed |
| EP-1117659-A1 | SUBSTITUTED 3-CYANOQUINOLINES AS PROTEIN TYROSINE KINASES INHIBITORS | American Cyanamid Company (US) | 2001-07-25 | — | — | EP | claimed |
| WO-2000059880-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-10-12 | — | — | WO | claimed |
| US-6110922-A | ARYL SULFIDE CONTAINING PENDANT CIS- OR TRANS-CINNAMIDE GROUPS | ABBOTT LABORATORIES (US) | 2000-08-29 | — | — | US | claimed |
| WO-2000039081-A2 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-07-06 | — | — | WO | claimed |
| EP-1000060-A1 | NOVEL COMPOUNDS | AstraZeneca UK Limited (GB) | 2000-05-17 | — | — | EP | claimed |
| WO-2000018761-A1 | SUBSTITUTED 3-CYANOQUINOLINES AS PROTEIN TYROSINE KINASES INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 2000-04-06 | — | — | WO | claimed |
| WO-1999002528-A1 | NOVEL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1999-01-21 | — | — | WO | claimed |
| US-5714493-A | ANTIINFLAMMATORY AGENT | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1998-02-03 | — | — | US | claimed |
| EP-0677516-A1 | Cyclic amide derivatives | Eisai Co., Ltd. (JP) | 1995-10-18 | — | — | EP | claimed |
| EP-0468187-A2 | Cyclic amide derivatives | Eisai Co., Ltd. (JP) | 1992-01-29 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090317440-A1 | ANTI-MITOTIC ANTI-PROLIFERATIVE COMPOUNDS | MKI67, PCNA, CCNB2 | ATM 936/4885EGFR 3418/4885HSP90AA1 2057/4885 |
| US-20120149744-A1 | ANTI-MITOTIC ANTI-PROLIFERATIVE COMPOUNDS | MKI67, PCNA, CCNB2 | ATM 936/4885EGFR 3418/4885HSP90AA1 2057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.