Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | TACR3 | P29371 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RUVBL1 | Q9Y265 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602177 | 0.93 | TRPV1 (0.49) | CDK2LMNASMN1; SMN2MAPTPTBP1 | |
| Tryptophanol SCHEMBL5155681 | 0.86 | TACR3 (0.45) | LMNASMN1; SMN2MAPTDHODHTACR3 | |
| Tryptophanol SCHEMBL5155750 | 0.86 | MEN1 (0.48) | LMNASMN1; SMN2MAPTHTTDHODH | |
| SCHEMBL5154442 | 0.85 | TACR3 (0.57) | LMNASMN1; SMN2MAPTHTTTACR3 | |
| SCHEMBL14557585 | 0.81 | ITGB2 (0.42) | CDK2LMNASMN1; SMN2MAPTPTBP1 | |
| SCHEMBL4601284 | 0.81 | TACR3 (0.53) | LMNASMN1; SMN2MAPTHTTTACR3 | |
| SCHEMBL14557563 | 0.81 | KDM4E (0.56) | LMNASMN1; SMN2MAPTTACR3TP53 | |
| SCHEMBL4601942 | 0.79 | ITGB2 (0.50) | LMNASMN1; SMN2MAPTTACR3TP53 | |
| SCHEMBL4600729 | 0.79 | TACR3 (0.49) | MAPTTACR3ALDH1A1HPGD | |
| SCHEMBL4602563 | 0.79 | KDM4E (0.57) | LMNASMN1; SMN2MAPTHTTDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | FSHR, NPY1R, NPY2R | CDK2 1146/4885LMNA 3198/4885SMN1; SMN2 3867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.