SCHEMBL5154675

SCHEMBL5154675

Oc1cnc(O)o1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5154398 0.71
SCHEMBL5154572 0.71
SCHEMBL9963871 0.67 CDK2 (0.34)
SCHEMBL3087189 0.53
SCHEMBL4584646 0.53
SCHEMBL276486 0.50
SCHEMBL3642541 0.50
SCHEMBL5041090 0.48 KDM4E (0.35)
SCHEMBL6718539 0.38
SCHEMBL10338943 0.35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105392824-B The preparation method of new branch oligomeric aryl-silane and they 发光创新科技有限责任公司 2018-09-28 CN claimed
US-7297168-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2007-11-20 US claimed
US-20050198745-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-09-15 US claimed
CN-114555573-A Prostaglandin E2(PGE2)EP4Receptor antagonists 多曼治疗学公司 2022-05-27 CN disclosed
CN-113631686-A Liquid crystal compounds 罗利克技术有限公司 2021-11-09 CN disclosed
CN-109790189-A The reactive mesogen coughed up based on dibenzo [D, B] thiophene 洛马克斯有限公司 2019-05-21 CN disclosed
CN-105517574-B The combination product of hepatitis C virus inhibitors 百时美施贵宝公司 2019-01-18 CN disclosed
CN-105392824-B The preparation method of new branch oligomeric aryl-silane and they 发光创新科技有限责任公司 2018-09-28 CN disclosed
CN-104302290-B Hepatitis c virus inhibitors 百时美施贵宝公司 2017-10-24 CN disclosed
CN-104703980-B Belong to the orexin receptor antagonists of [adjacent double (miscellaneous) aryl] [base of 2 (double (miscellaneous) aryl) pyrrolidines 1] ketone derivatives 埃科特莱茵药品有限公司 2017-09-22 CN disclosed
CN-102459165-A Anti-viral compounds ABBOTT LAB 2012-05-16 CN disclosed
US-7297168-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2007-11-20 US disclosed
EP-1737417-A2 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF The Procter and Gamble Company (US) 2007-01-03 EP disclosed
US-20050198745-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-09-15 US disclosed
WO-2005074875-A2 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2005-08-18 WO disclosed