Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 19/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4934777 | 0.94 | PDE4B (0.64) | PDE4B | |
| SCHEMBL4934822 | 0.94 | PDE4B (0.64) | PDE4B | |
| SCHEMBL4937907 | 0.94 | PDE4B (0.64) | PDE4B | |
| SCHEMBL4931313 | 0.94 | PDE4B (0.64) | PDE4B | |
| Hydrochloric Acid SCHEMBL4932521 | 0.94 | PDE4B (0.63) | PDE4B | |
| SCHEMBL4935669 | 0.90 | PDE4B (0.66) | PDE4B | |
| SCHEMBL4934826 | 0.88 | PDE4B (0.64) | PDE4B | |
| SCHEMBL4927710 | 0.87 | PDE4B (0.59) | PDE4B | |
| SCHEMBL4935807 | 0.87 | PDE4B (0.59) | PDE4B | |
| SCHEMBL4932499 | 0.86 | PDE4B (0.65) | PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737857-A1 | PYRAZOLO[3,4-B] PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005058892-A1 | PYRAZOLO [3,4-B] PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2005-06-30 | — | — | WO | disclosed |