Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 20/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 18/20 | 0.37 |
| ▸ | DRD2 | P14416 | 17/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL4880723 | 0.82 | DRD3 (0.51) | DRD3KCNH2DRD2 | |
| SCHEMBL4880728 | 0.82 | DRD3 (0.39) | DRD3KCNH2DRD2 | |
| SCHEMBL4867467 | 0.59 | DRD3 (0.51) | DRD3KCNH2DRD2 | |
| SCHEMBL4879702 | 0.59 | DRD3 (0.53) | DRD3KCNH2DRD2 | |
| Formic Acid SCHEMBL4879696 | 0.59 | DRD3 (0.69) | DRD3KCNH2DRD2 | |
| Formic Acid SCHEMBL4880108 | 0.58 | DRD3 (0.70) | DRD3KCNH2DRD2 | |
| SCHEMBL4881765 | 0.58 | DRD3 (0.56) | DRD3KCNH2DRD2 | |
| SCHEMBL4880857 | 0.58 | DRD3 (0.51) | DRD3KCNH2DRD2 | |
| SCHEMBL4877762 | 0.58 | DRD3 (0.66) | DRD3KCNH2DRD2 | |
| Formic Acid SCHEMBL4881761 | 0.57 | DRD3 (0.70) | DRD3KCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737851-A1 | TETRAHYDROBENZAZEPINE DERIVATIVES AS MODULATORS OF DOPAMINE D3 RECEPTORS (ANTIPSYCHOTIC AGENTS) | GLAXO GROUP LIMITED (GB) | 2007-01-03 | — | — | EP | claimed |
| WO-2005087764-A1 | TETRAHYDROBENZAZEPINE DERIVATIVES AS MODULATORS OF DOPAMINE D3 RECEPTORS (ANTIPSYCHOTIC AGENTS) | GLAXO GROUP LIMITED (GB) | 2005-09-22 | — | — | WO | claimed |