SCHEMBL5154850

SCHEMBL5154850

CC(N1C(=O)CCC1=O)N(C(C)N1C(=O)CCC1=O)C(C)N1C(=O)CCC1=O

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
CHRM1 P11229 1/20 0.36
CHRM3 P20309 1/20 0.36
SLC1A2 P43004 1/20 0.33
PIK3CD O00329 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7052300 0.75 SLC1A2 (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL1698550 0.75 SMN1; SMN2 (0.41) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL10644061 0.72 CHRM2 (0.38) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL6050180 0.70 CHRM2 (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL19286980 0.70 CHRM2 (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL10797503 0.70 CHRM2 (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL8749736 0.70 CHRM2 (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL1536266 0.70 CHRM2 (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL22372501 0.70 CHRM2 (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL10769736 0.70 CHRM2 (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0762901-B9 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING CIS BIO INT (FR) 2007-01-17 EP claimed
EP-0637968-B2 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING DIATIDE INC (US) 2006-07-26 EP claimed
EP-0684843-B1 TECHNETIUM-99m LABELED PEPTIDES FOR DIAGNOSTIC IMAGING OF INFLAMMATION DIATIDE INC (US) 2006-05-10 EP claimed
EP-0762901-B1 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING BERLEX INC (US) 2006-04-19 EP claimed
EP-1583565-A1 ENHANCED SCINTIGRAPHIC IMAGING AGENTS FOR IMAGING OF INFECTION AND INFLAMMATION Schering AG (DE) 2005-10-12 EP claimed
US-20050002861-A1 Enhanced scintigraphic imaging agents for imaging of infection and inflammation BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2005-01-06 US claimed
EP-0775160-B1 CYCLIC HEXAPEPTIDE SOMATOSTATIN ANALOGUES DIATIDE INC (US) 2004-08-18 EP claimed
WO-2004060409-A1 ENHANCED SCINTIGRAPHIC IMAGING AGENTS FOR IMAGING OF INFECTION AND INFLAMMATION SCHERING AG (DE) 2004-07-22 WO claimed
EP-1437145-A1 Enhanced scintigraphic imaging agents for imaging of infection and inflammation Schering AG (DE) 2004-07-14 EP claimed
EP-0804481-B1 SOMATOSTATIN DERIVATIVES AND THEIR RADIOLABELLED PRODUCTS DIATIDE INC (US) 2003-04-16 EP claimed
EP-0637968-A1 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING Diatide, Inc. (US) 1995-02-15 EP claimed
WO-1995000553-A1 RADIOLABELED SOMATOSTATIN-DERIVED PEPTIDES FOR IMAGING AND THERAPEUTIC USES DIATECH, INC. (US) 1995-01-05 WO claimed
WO-1994023758-A1 RADIOLABELED COMPOUNDS FOR THROMBUS IMAGING DIATECH, INC. (US) 1994-10-27 WO claimed
WO-1994019024-A2 TECHNETIUM-99m LABELED PEPTIDES FOR DIAGNOSTIC IMAGING DIATECH, INC. (US) 1994-09-01 WO claimed
WO-1994007918-A1 MULTIMERIC POLYVALENT ANTITHROMBOTIC AGENTS DIATECH, INC. (US) 1994-04-14 WO claimed
WO-1994000489-A2 RADIOACTIVELY-LABELED SOMATOSTANTIN-DERIVED PEPTIDES FOR IMAGING AND THERAPEUTIC USES DIATECH, INC. (US) 1994-01-06 WO claimed
WO-1993025244-A1 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING DIATECH, INC. (US) 1993-12-23 WO claimed
WO-1993023085-A1 TECHNETIUM-99m LABELED PEPTIDES FOR THROMBUS IMAGING DIATECH, INC. (US) 1993-11-25 WO claimed
WO-1993021962-A1 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING DIATECH, INC. (US) 1993-11-11 WO claimed
WO-1993017719-A1 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING INFLAMMATION DIATECH, INC. (US) 1993-09-16 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050002861-A1 Enhanced scintigraphic imaging agents for imaging of infection and inflammation SIGLEC7, CD209, SIGLEC9 CHRM2 4629/4885CHRM4 3997/4885CHRM5 3805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.