SCHEMBL515527

SCHEMBL515527

CCC1(NC(C)C(=O)O)CCCCC1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MME P08473 4/20 0.44
LTA4H P09960 2/20 0.37
CETP P11597 5/20 0.35
SMN1; SMN2 Q16637 1/20 0.33
RAB9A P51151 1/20 0.33
ACE P12821 1/20 0.33
CPA1 P15085 1/20 0.33
ACE2 Q9BYF1 1/20 0.33
FAAH O00519 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3725757 1.00 MME (0.44) MMELTA4HCETPSMN1; SMN2RAB9A
SCHEMBL14742983 0.98 MME (0.45) MMELTA4HCETPSMN1; SMN2RAB9A
SCHEMBL5857636 0.84 MME (0.42) MMELTA4HSMN1; SMN2RAB9A
SCHEMBL25901525 0.78 MME (0.33) MMESMN1; SMN2RAB9AACECPA1
SCHEMBL17181685 0.77 MME (0.42) MMELTA4HSMN1; SMN2RAB9A
SCHEMBL997755 0.77 MME (0.42) MMELTA4HSMN1; SMN2RAB9A
SCHEMBL19347273 0.76 CETP (0.32) CETP
SCHEMBL13070545 0.75
SCHEMBL158231 0.75 MME (0.43) MMELTA4HCETPSMN1; SMN2RAB9A
SCHEMBL6037209 0.75 MME (0.43) MMELTA4HCETPSMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250188150-A1 PEPTIDES FOR THE TREATMENT OF FIBROSIS TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2025-06-12 US disclosed
US-20240398906-A1 PROPEPTIDE OF LYSYL OXIDASE FOR TREATMENT OF CANCER YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2024-12-05 US disclosed
US-20240182532-A1 MICROPEPTIDES AND USES THEREOF FUNDACIÓ PRIVADA INSTITUT D'INVESTIGACIÓ ONCOLÒGICA DE VALL HEBRON (ES) 2024-06-06 US disclosed
US-11858972-B2 Micropeptides and uses thereof FUNDACIÓ PRIVADA INSTITUT D'INVESTIGACIÓ ONCOLÒGICA DE VALL HEBRON (ES) 2024-01-02 US disclosed
US-20220251153-A1 PEPTIDES FOR THE TREATMENT OF RENAL DISORDERS UGH PHARMA, INC. (PA) 2022-08-11 US disclosed
US-20220120732-A1 TREATMENT OF DISEASES WITH MULTIMERIC PEPTIDES RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2022-04-21 US disclosed
US-20220049236-A1 COMPOSITIONS COMPRISING THE PROPEPTIDE OF LYSYL OXIDASE AND USES THEREOF YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2022-02-17 US disclosed
US-20210162025-A1 VARIANTS OF TACE PRO-DOMAIN AS TNF-A INHIBITOR AND THEIR MEDICAL USE YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2021-06-03 US disclosed
US-10933122-B2 Variants of TACE pro-domain as TNF-A inhibitor and their medical use YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2021-03-02 US disclosed
US-10906937-B2 Peptides and compositions comprising same and uses thereof in the treatment of diseases ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) 2021-02-02 US disclosed
US-20100298226-A1 POLYPEPTIDES AND POLYNUCLEOTIDES ENCODING SAME AND USE THEREOF IN THE TREATMENT OF MEDICAL CONDITIONS ASSOCIATED WITH ISCHEMIA VASCULAR BIOGENICS LTD. (IL) 2010-11-25 US disclosed
US-20100279943-A1 CYTOPLASMIC MALATE DEHYDROGENASE (MDH1) TARGETED TREATMENT FOR NEURODEGENERATIVE DISEASES RAMAT AT TEL AVIV UNIVERSITY LTD. (IL) 2010-11-04 US disclosed
CN-101820897-A Cytoplasmic malate dehydrogenase (MDH1) targeted treatment for neurodegenerative diseases UNIV RAMOT 2010-09-01 CN disclosed
US-20100203609-A1 PHOTOCATALYTIC HYDROGEN PRODUCTION AND POLYPEPTIDES CAPABLE OF SAME RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2010-08-12 US disclosed
US-20100104607-A1 ANTI-BACTERIAL PEPTIDES AND METHODS OF TREATING DISEASES USING SAME YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2010-04-29 US disclosed
US-20100093600-A1 REGULATION OF NEUROTRANSMITTERS SEQUESTRATION AND RELEASE THROUGH MANIPULATION OF THE VESICULAR FUNCTIONS RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2010-04-15 US disclosed
US-20090305970-A1 Toxin-Like Polypeptides, Polynucleotides Encoding Same and Uses Thereof YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2009-12-10 US disclosed
US-20090242879-A1 Optoelectronic device and method of fabricating the same RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2009-10-01 US disclosed
US-7524929-B2 polypeptides comprising an amino acid sequence of a photocatalytic unit of a photosynthetic microorganism, capable of maintaining photocatalytic activity when attached to solid surfaces of electrooptic devices RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2009-04-28 US disclosed
US-20080305471-A1 polypeptides comprising an amino acid sequence of a photocatalytic unit of a photosynthetic microorganism, capable of maintaining photocatalytic activity when attached to solid surfaces of electrooptic devices RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2008-12-11 US disclosed