⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL516582 | 0.76 | TSHR (0.33) | — | |
| SCHEMBL703269 | 0.76 | TSHR (0.33) | — | |
| SCHEMBL4132422 | 0.75 | — | — | |
| SCHEMBL382997 | 0.72 | TSHR (0.35) | — | |
| SCHEMBL25289015 | 0.71 | — | — | |
| SCHEMBL1935002 | 0.71 | — | — | |
| SCHEMBL26907984 | 0.71 | — | — | |
| SCHEMBL10390791 | 0.71 | — | — | |
| SCHEMBL647352 | 0.71 | — | — | |
| SCHEMBL647354 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4695384-A2 | COMPOSITIONS AND METHODS FOR UPREGULATION OF REVERSE TRANSCRIPTION AND REDUCTION OF SEQUENCE BIAS IN RNA SEQUENCING | 5Prime Biosciences, Inc. (US) | 2026-02-18 | — | — | EP | claimed |
| WO-2024216275-A2 | COMPOSITIONS AND METHODS FOR UPREGULATION OF REVERSE TRANSCRIPTION AND REDUCTION OF SEQUENCE BIAS IN RNA SEQUENCING | 5PRIME BIOSCIENCES, INC. (US) | 2024-10-17 | — | — | WO | claimed |
| EP-4413125-A1 | POLYMERASES FOR MIXED AQUEOUS-ORGANIC MEDIA AND USES THEREOF | 5Prime Biosciences, Inc. (US) | 2024-08-14 | — | — | EP | claimed |
| US-20240150820-A1 | ASSESSMENT OF BIOLOGICAL PARTICLES IMMOBILIZED IN A HYDROGEL | CHEMOMETEC A/S (DK) | 2024-05-09 | — | — | US | claimed |
| EP-4305197-A1 | ASSESSMENT OF BIOLOGICAL PARTICLES IMMOBILIZED IN A HYDROGEL | ChemoMetec A/S (DK) | 2024-01-17 | — | — | EP | claimed |
| WO-2023059361-A1 | POLYMERASES FOR MIXED AQUEOUS-ORGANIC MEDIA AND USES THEREOF | 5PRIME BIOSCIENCES, INC. (US) | 2023-04-13 | — | — | WO | claimed |
| WO-2023005843-A1 | METHOD FOR PREPARING RNA, METHOD FOR SYNTHESIZING PROTEIN, AND TRANSCRIPTION REACTION SOLUTION | 上海兆维科技发展有限公司 | 2023-02-02 | — | — | WO | claimed |
| CN-115505589-A | Preparation method of RNA, method for synthesizing protein and transcription reaction solution | 上海兆维科技发展有限公司 | 2022-12-23 | — | — | CN | claimed |
| WO-2022189645-A1 | ASSESSMENT OF BIOLOGICAL PARTICLES IMMOBILIZED IN A HYDROGEL | CHEMOMETEC A/S (DK) | 2022-09-15 | — | — | WO | claimed |
| CN-113584014-A | Preparation method of RNA, method for synthesizing protein and transcription reaction solution | 上海兆维科技发展有限公司 | 2021-11-02 | — | — | CN | claimed |
| US-20090215888-A1 | TOPICAL NAIL FORMULATION | NUVO RESEARCH INC. (CA) | 2009-08-27 | — | — | US | claimed |
| EP-1909772-A1 | TRANSDERMAL DRUG DELIVERY FORMULATION | Nuvo Research Inc. (CA) | 2008-04-16 | — | — | EP | claimed |
| WO-2007098591-A2 | TOPICAL NAIL FORMULATION | NUVO RESEARCH INC. (CA) | 2007-09-07 | — | — | WO | claimed |
| WO-2007016766-A1 | TRANSDERMAL DRUG DELIVERY FORMULATION | NUVO RESEARCH INC. (CA) | 2007-02-15 | — | — | WO | claimed |
| US-6949368-B2 | Compositions and methods for enhancing polynucleotide amplification reactions | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2005-09-27 | — | — | US | claimed |
| US-20030039992-A1 | Compositions and methods for enhancing polynucleotide amplification reactions | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-02-27 | — | — | US | claimed |
| WO-2002061137-A2 | COMPOSITIONS AND METHODS FOR ENHANCING POLYNUCLEOTIDE AMPLIFICATION REACTIONS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2002-08-08 | — | — | WO | claimed |
| EP-4695384-A2 | COMPOSITIONS AND METHODS FOR UPREGULATION OF REVERSE TRANSCRIPTION AND REDUCTION OF SEQUENCE BIAS IN RNA SEQUENCING | 5Prime Biosciences, Inc. (US) | 2026-02-18 | — | — | EP | disclosed |
| EP-0636615-A1 | 2-ARYLAMINOPYRIMIDINONE DERIVATIVE, AND HERBICIDE AND PLANT GROWTH REGULATOR | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1995-02-01 | — | — | EP | disclosed |
| EP-0546409-A1 | Method for the preparation of tetrahydropyrancarboxylic esters | BASF Aktiengesellschaft (DE) | 1993-06-16 | — | — | EP | disclosed |