⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21026422 | 0.71 | — | — | |
| SCHEMBL19007328 | 0.67 | — | — | |
| SCHEMBL28841868 | 0.67 | DAO (0.32) | — | |
| SCHEMBL24091386 | 0.67 | — | — | |
| SCHEMBL5175439 | 0.67 | — | — | |
| SCHEMBL28127490 | 0.67 | — | — | |
| SCHEMBL23241465 | 0.63 | — | — | |
| SCHEMBL25421633 | 0.62 | — | — | |
| SCHEMBL12778243 | 0.62 | — | — | |
| SCHEMBL7253514 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050198745-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-15 | — | — | US | claimed |
| WO-2023014793-A1 | PROCESS FOR POLYAMIDE SYNTHESIS | Design Therapeutics, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |
| CN-110038134-A | The Nano medication transmission system and preparation method of double responsiveness carrying anti-tumor drug for oncotherapy | 南开大学 | 2019-07-23 | — | — | CN | disclosed |
| CN-108239071-A | Amide and thioamides analog derivative and its preparation method and application | 沈阳药科大学 | 2018-07-03 | — | — | CN | disclosed |
| CN-105503837-B | Substituted quinazoline analog derivative and its application with Aurora kinase inhibitory activity | 中山大学 | 2018-06-29 | — | — | CN | disclosed |
| CN-108191822-A | A kind of synthetic method of Rynaxypyr | 广东丸美生物技术股份有限公司 | 2018-06-22 | — | — | CN | disclosed |
| EP-3208269-A1 | INHIBITORS OF C-FMS KINASE | Janssen Pharmaceutica N.V. (BE) | 2017-08-23 | — | — | EP | disclosed |
| CN-104844567-B | Synthesis method of intermediate 1- (3-chloro-2-pyridyl) -3-bromo-1H-5-pyrazolecarboxylic acid | 暨南大学 | 2017-03-29 | — | — | CN | disclosed |
| WO-2013017714-A1 | HIGH-TEMPERATURE ORGANOGELLING COMPOUNDS | UNIVERSITAT JAUME I DE CASTELLÓ (ES) | 2013-02-07 | — | — | WO | disclosed |
| WO-2011050160-A1 | PHARMACEUTICALS, COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME | BIOGEN IDEC MA INC. (US) | 2011-04-28 | — | — | WO | disclosed |
| US-7297168-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-11-20 | — | — | US | disclosed |
| EP-1737417-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter and Gamble Company (US) | 2007-01-03 | — | — | EP | disclosed |
| US-20050198745-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-15 | — | — | US | disclosed |
| WO-2005074875-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2005-08-18 | — | — | WO | disclosed |
| EP-0341493-A2 | Optically active pyridonecarboxylic acid derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1989-11-15 | — | — | EP | disclosed |