SCHEMBL5157510

SCHEMBL5157510

CCCCOC(=O)c1ccc(-c2ccc(C(=O)OCCCC)c(C(=O)O)c2)cc1C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.63
TDP1 Q9NUW8 2/20 0.63
L3MBTL1 Q9Y468 2/20 0.63
MAPK1 P28482 3/20 0.57
CYP3A4 P08684 3/20 0.57
TP53 P04637 1/20 0.57
ALDH1A1 P00352 4/20 0.56
LMNA P02545 3/20 0.55
HSD17B10 Q99714 1/20 0.51
RARA P10276 1/20 0.51
RARB P10826 1/20 0.51
PTPN11 Q06124 3/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
ESR1 P03372 2/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C19 P33261 2/20 0.47
CYP2D6 P10635 1/20 0.47
NR1H2 P55055 1/20 0.47
RNASEL Q05823 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5157413 0.98 TSHR (0.61) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL6938963 0.97 TSHR (0.59) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL6938958 0.94 TSHR (0.58) TSHRTDP1L3MBTL1MAPK1CYP3A4
Hydrochloric Acid SCHEMBL6941383 0.92 TSHR (0.57) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL10653835 0.90 TSHR (0.66) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL13737267 0.86 TSHR (0.61) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL4138132 0.86 TSHR (0.61) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL27261457 0.86 TSHR (0.61) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL301822 0.86 TSHR (0.61) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL31633208 0.86 TSHR (0.61) TSHRTDP1L3MBTL1MAPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1013650-B1 Tetracarboxylic dianhydride, derivative and production thereof, polyimide precursor, polyimide, resin composition, photosensitive resin composition, method of forming relief pattern, and electronic part HITACHI CHEM DUPONT MICROSYS (JP) 2007-01-24 EP disclosed
US-6600053-B2 Useful for producing polyimide precursors or polyimides having low thermal expansion and low residual stress HITACHI CHEMICAL DUPONT MICROSYSTEMS LTD. (JP) 2003-07-29 US disclosed
US-20020037991-A1 Photosensitive resin composition HITACHI CHEMICAL DUPONT MICROSYSTEMS LTD. (JP) 2002-03-28 US disclosed
US-6329494-B1 HIGH-SPEED DEVELOPABILITY, HIGH RESOLUTION AND GOOD DIMENSIONAL ACCURACY TO SUIT THEM TO THE PRODUCTION OF INTERLAYER INSULATING FILMS OR SURFACE-PROTECTING FILMS IN SEMICONDUCTOR DEVICES HITACHI CHEMICAL DUPONT MICROSYSTEMS LTD. (JP) 2001-12-11 US disclosed
EP-1013650-A2 Tetracarboxylic dianhydride, derivative and production thereof, polyimide precursor, polyimide, resin composition, photosensitive resin composition, method of forming relief pattern, and electronic part Hitachi Chemical DuPont MicroSystems Ltd. (JP) 2000-06-28 EP disclosed