Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 9/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.44 |
| ▸ | MGLL | Q99685 | 6/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5153014 | 1.00 | GCGR (0.47) | GCGRESR1ESR2MGLLHSD17B1 | |
| SCHEMBL5153007 | 1.00 | GCGR (0.47) | GCGRESR1ESR2MGLLHSD17B1 | |
| SCHEMBL22309429 | 0.83 | ERN1 (0.37) | GCGRESR1ESR2ERN1 | |
| SCHEMBL14580131 | 0.83 | TLR8 (0.46) | GCGRESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL5156136 | 0.82 | ESR1 (0.52) | GCGRESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL4898305 | 0.80 | ESR1 (0.48) | ESR1ESR2MGLLHSD17B1HSD17B2 | |
| SCHEMBL4898311 | 0.80 | ESR1 (0.48) | ESR1ESR2MGLLHSD17B1HSD17B2 | |
| SCHEMBL15542687 | 0.79 | ESR1 (0.47) | ESR1ESR2MGLLHSD17B1HSD17B2 | |
| SCHEMBL29576668 | 0.79 | ESR1 (0.47) | ESR1ESR2MGLLHSD17B1HSD17B2 | |
| SCHEMBL17353846 | 0.79 | ESR1 (0.47) | ESR1ESR2MGLLHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633699-B1 | ARYL-CARBALDEHYDE OXIME DERIVATIVES AND THEIR USE AS ESTROGENIC AGENTS | WYETH CORP (US) | 2007-01-03 | — | — | EP | claimed |