Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9420994 | 0.85 | TSHR (0.46) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL30584 | 0.84 | — | — | |
| SCHEMBL3647636 | 0.84 | TSHR (0.44) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL20183950 | 0.84 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL8997902 | 0.83 | TSHR (0.56) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL15347093 | 0.83 | TSHR (0.61) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Ethylene SCHEMBL27563966 | 0.82 | TSHR (0.60) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL7154955 | 0.81 | — | — | |
| SCHEMBL9614626 | 0.81 | TSHR (0.59) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL27523038 | 0.79 | TSHR (0.62) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745081-A1 | POLYSILOXANE GRAFT POLYMER | Wacker Chemie AG (DE) | 2007-01-24 | — | — | EP | claimed |
| WO-2005108449-A1 | POLYSILOXANE GRAFT POLYMER | WACKER CHEMIE AG (DE) | 2005-11-17 | — | — | WO | claimed |
| EP-1745081-A1 | POLYSILOXANE GRAFT POLYMER | Wacker Chemie AG (DE) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005108449-A1 | POLYSILOXANE GRAFT POLYMER | WACKER CHEMIE AG (DE) | 2005-11-17 | — | — | WO | disclosed |