SCHEMBL515859

SCHEMBL515859

Cc1ccc2oc(/C=C/c3ccc(-c4nc5cc(C)ccc5o4)cc3)nc2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.68
SMN1; SMN2 Q16637 9/20 0.68
NPC1 O15118 9/20 0.68
RAB9A P51151 9/20 0.68
ALDH1A1 P00352 9/20 0.68
HPGD P15428 8/20 0.68
HSD17B10 Q99714 7/20 0.68
TP53 P04637 6/20 0.68
CASP3 P42574 3/20 0.61
SENP7 Q9BQF6 3/20 0.61
SENP6 Q9GZR1 3/20 0.61
SENP8 Q96LD8 2/20 0.61
POLB P06746 1/20 0.61
SNCA P37840 1/20 0.59
MMP2 P08253 1/20 0.55
MMP9 P14780 1/20 0.55
MMP8 P22894 1/20 0.55
MMP13 P45452 1/20 0.55
NFKB1 P19838 5/20 0.55
NFKB2 Q00653 5/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29881920 1.00 KDM4E (0.68) KDM4ESMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL318305 1.00 KDM4E (0.68) KDM4ESMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL28820725 0.94 NPC1 (0.61) KDM4ESMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL29360251 0.93 KDM4E (0.79) KDM4ESMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL385476 0.93 KDM4E (0.79) KDM4ESMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL385477 0.93 KDM4E (0.79) KDM4ESMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL1248209 0.92 KDM4E (0.82) KDM4ESMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL15951017 0.89 SMN1; SMN2 (0.54) KDM4ESMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL15951018 0.89 SMN1; SMN2 (0.54) KDM4ESMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL27791454 0.89 KDM4E (0.54) KDM4ESMN1; SMN2NPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101120046-B Molded article exhibiting multi-color effects, associated lighting device and resin ARKEMA FRANCE 2011-02-23 CN claimed
US-20080214706-A1 Moulded Object Exhibiting a Polychromatic Effect, Associated Light Device and Resin ARKEMA FRANCE (FR) 2008-09-04 US claimed
EP-1848763-B1 MOULDED OBJECT EXHIBITING A POLYCHROMATIC EFFECT, ASSOCIATED LIGHT DEVICE AND RESIN ARKEMA FRANCE (FR) 2008-04-16 EP claimed
CN-101120046-A Molded article exhibiting multi-color effects, associated lighting device and resin ARKEMA FRANCE (FR) 2008-02-06 CN claimed
EP-1848763-A1 MOULDED OBJECT EXHIBITING A POLYCHROMATIC EFFECT, ASSOCIATED LIGHT DEVICE AND RESIN Arkema France (FR) 2007-10-31 EP claimed
WO-2006087241-A1 MOULDED OBJECT EXHIBITING A POLYCHROMATIC EFFECT, ASSOCIATED LIGHT DEVICE AND RESIN ARKEMA FRANCE (FR) 2006-08-24 WO claimed
US-5142343-A An electroluminiscent oligomer semiconductor zone and an insulator zone containing a light-emitting zone sandwiched between electrodes IDEMITSU KOSAN CO., LTD. (JP) 1992-08-25 US claimed
US-12303582-B2 Composition for the treatment of nail fungus OYSTERSHELL NV (BE) 2025-05-20 US disclosed
US-11871590-B2 Thin film of metal oxide, organic electroluminescent device including thin film, photovoltaic cell including thin film, and manufacturing method of thin film JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2024-01-09 US disclosed
US-20210343961-A1 THIN FILM OF METAL OXIDE, ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THIN FILM, PHOTOVOLTAIC CELL INCLUDING THIN FILM, AND MANUFACTURING METHOD OF THIN FILM JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2021-11-04 US disclosed
US-20210299022-A1 COMPOSITION FOR THE TREATMENT OF NAIL FUNGUS OYSTERSHELL NV (BE) 2021-09-30 US disclosed
EP-3884933-A1 COMPOSITION FOR THE TREATMENT OF NAIL FUNGUS Oystershell NV (BE) 2021-09-29 EP disclosed
US-11094909-B2 Thin film of metal oxide, organic electroluminescent device including the thin film, photovoltaic cell including the thin film and organic photovoltaic cell including the thin film JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2021-08-17 US disclosed
US-5314775-A Electroluminescence device as charge transfer compound MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1994-05-24 US disclosed
EP-0563811-A1 Silanamine derivative and process for the production thereof, and organical EL device using the said silanamine derivative IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-10-06 EP disclosed
EP-0548366-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-06-30 EP disclosed
US-5142343-A An electroluminiscent oligomer semiconductor zone and an insulator zone containing a light-emitting zone sandwiched between electrodes IDEMITSU KOSAN CO., LTD. (JP) 1992-08-25 US disclosed
EP-0439627-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-08-07 EP disclosed
EP-0120673-B1 ORGANIC ELECTROLUMINESCENT DEVICES HAVING IMPROVED POWER CONVERSION EFFICIENCIES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-06-01 EP disclosed
US-4539507-A CHARGE TRANSFER COMPOUNDS EASTMAN KODAK COMPANY (US) 1985-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12303582-B2 Composition for the treatment of nail fungus DPM1, PIK3C3, ETF1 KDM4E 1587/4885SMN1; SMN2 3362/4885NPC1 1932/4885
US-20210299022-A1 COMPOSITION FOR THE TREATMENT OF NAIL FUNGUS DPM1, PIK3C3, ETF1 KDM4E 1587/4885SMN1; SMN2 3362/4885NPC1 1932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.